22 Recruiting Studies Using Irinotecan Hydrochloride
Active clinical trials that use this intervention, sourced directly from the NIH registry.
Browse by conditionTrials Using Irinotecan Hydrochloride
NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer
📍 OHSU Knight Cancer Institute — Portland, Oregon
Pancreatic Adenocarcinoma
View Study & Checklist ➔Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver
📍 Memorial Sloan Kettering Cancer Center — Basking Ridge, New Jersey
Colorectal Cancer
View Study & Checklist ➔Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer
📍 Mayo Clinic Hospital in Arizona — Phoenix, Arizona
Metastatic Lung Small Cell Carcinoma
View Study & Checklist ➔Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines
📍 City of Hope Comprehensive Cancer Center — Duarte, California
Advanced Colorectal Carcinoma
View Study & Checklist ➔Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
📍 Children's Hospital of Alabama — Birmingham, Alabama
Alveolar Rhabdomyosarcoma
View Study & Checklist ➔Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer
📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama
Colorectal Adenocarcinoma
View Study & Checklist ➔Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma
📍 Memorial Sloan Kettering Cancer Center — New York, New York
Sarcoma
View Study & Checklist ➔Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas
📍 City of Hope Medical Center — Duarte, California
Recurrent Anaplastic Astrocytoma
View Study & Checklist ➔Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma
📍 Children's Hospital of Alabama — Birmingham, Alabama
High Risk Neuroblastoma
View Study & Checklist ➔Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
📍 Sidney Kimmel Cancer Center at Thomas Jefferson University — Philadelphia, Pennsylvania
Locally Advanced Pancreatic Ductal Adenocarcinoma
View Study & Checklist ➔Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
📍 Children's Hospital of Alabama — Birmingham, Alabama
CIC-Rearranged Sarcoma
View Study & Checklist ➔M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
📍 Los Angeles General Medical Center — Los Angeles, California
Metastatic Colorectal Carcinoma
View Study & Checklist ➔Erlotinib Hydrochloride and Irinotecan Hydrochloride in Treating Patients With Advanced Solid Tumors
📍 Mayo Clinic in Rochester — Rochester, Minnesota
Adult Solid Neoplasm
View Study & Checklist ➔Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer
📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama
Pancreatic Adenosquamous Carcinoma
View Study & Checklist ➔Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial
📍 CTCA at Western Regional Medical Center — Goodyear, Arizona
Metastatic Appendix Carcinoma
View Study & Checklist ➔Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
📍 Anchorage Associates in Radiation Medicine — Anchorage, Alaska
Metastatic Small Intestinal Adenocarcinoma
View Study & Checklist ➔A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)
📍 Children's Hospital of Alabama — Birmingham, Alabama
Rhabdomyosarcoma
View Study & Checklist ➔A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
📍 Banner MD Anderson Cancer Center — Gilbert, Arizona
Colorectal Neoplasms
View Study & Checklist ➔Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
Neuroblastoma
View Study & Checklist ➔A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
📍 Mayo Clinic Hospital — Phoenix, Arizona
Esophageal Squamous Cell Carcinoma
View Study & Checklist ➔Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer
📍 University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina
Pancreatic Ductal Adenocarcinoma (PDAC)
View Study & Checklist ➔Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
📍 Banner MD Anderson Cancer Center — Gilbert, Arizona
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
View Study & Checklist ➔