73 Recruiting Studies Using Letrozole
Active clinical trials that use this intervention, sourced directly from the NIH registry.
Browse by conditionTrials Using Letrozole
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
📍 Massachusetts General Hospital. — Boston, Massachusetts
Breast Cancer
View Study & Checklist ➔Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer
📍 Marin Cancer Care, Inc — Greenbrae, California
Breast Cancer
View Study & Checklist ➔OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer
📍 Clinical Trial Site — Tucson, Arizona
Breast Cancer
View Study & Checklist ➔An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
📍 Research Site — Dothan, Alabama
Breast Cancer, Early Breast Cancer
View Study & Checklist ➔Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer
📍 Univ of California at San Diego Moores Cancer Ctr — San Diego, California
Breast Cancer
View Study & Checklist ➔A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)
📍 Orange Coast Memorial Medical Center — Fountain Valley, California
Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
View Study & Checklist ➔Abemaciclib and Letrozole to Treat Endometrial Cancer
📍 University of South Alabama Mitchell Cancer Center — Mobile, Alabama
Endometrial Cancer
View Study & Checklist ➔Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer
📍 City of Hope Corona — Corona, California
Metastatic Breast Carcinoma
View Study & Checklist ➔S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama
Breast Cancer
View Study & Checklist ➔Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)
📍 Stamford Hospital — Stamford, Connecticut
Breast Cancer
View Study & Checklist ➔Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
📍 Northeast Alabama Regional Medical Center — Anniston, Alabama
Breast Ductal Carcinoma In Situ
View Study & Checklist ➔Roll-over Study to Allow Continued Access to Ribociclib
📍 Ironwood Cancer and Research Centers — Chandler, Arizona
Metastatic Breast Cancer
View Study & Checklist ➔A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
📍 Highlands Oncology Group - Duplicate 2 — Rogers, Arkansas
Breast Neoplasms
View Study & Checklist ➔Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
📍 Anchorage Associates in Radiation Medicine — Anchorage, Alaska
Low Grade Fallopian Tube Serous Adenocarcinoma
View Study & Checklist ➔Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer
📍 UCSF — San Francisco, California
HER-2 Positive Breast Cancer
View Study & Checklist ➔Extension Study of Lapatinib Plus Herceptin With or Without Endocrine Therapy
📍 University of Alabama - Birmingham — Birmingham, Alabama
Breast Cancer
View Study & Checklist ➔A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
📍 UCSF Helen Diller Family CCC — San Francisco, California
Ovarian Cancer
View Study & Checklist ➔Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
📍 Northeast Alabama Regional Medical Center — Anniston, Alabama
Breast Adenocarcinoma
View Study & Checklist ➔Neoadjuvant DPX-Survivac Aromatase Inhibition, Radiotherapy or Cyclophosphamide in HR+HER2- Breast Cancer
📍 Providence Portland Medical Center — Portland, Oregon
Breast Cancer
View Study & Checklist ➔Letrozole and RAD001 With Advanced or Recurrent Endometrial Cancer
📍 Morristown Memorial Hospital, Women's Cancer Center — Morristown, New Jersey
Endometrial Cancer
View Study & Checklist ➔Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer
📍 BRCR Global — Plantation, Florida
Breast Cancer
View Study & Checklist ➔TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer
📍 Stamford Hospital — Stamford, Connecticut
Breast Cancer
View Study & Checklist ➔Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
📍 Research Site — Phoenix, Arizona
ER-Positive HER2-Negative Breast Cancer
View Study & Checklist ➔Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
📍 Ellison Institute — Los Angeles, California
Liposarcoma
View Study & Checklist ➔Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
📍 University of Iowa Hospitals & Clinics - Davenport Clinic — Davenport, Iowa
Polycystic Ovary Syndrome
View Study & Checklist ➔Letrozole Plus Ribociclib or Placebo as Neo-adjuvant Therapy in ER-positive, HER2-negative Early Breast Cancer
📍 University of Arkansas for Medical Sciences — Little Rock, Arkansas
Breast Cancer
View Study & Checklist ➔A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma
📍 Lyndon Baines Johnson General Hospital — Houston, Texas
Recurrent Endometrial Carcinoma
View Study & Checklist ➔Ribociclib and Letrozole Treatment in Ovarian Cancer
📍 University of California, San Francisco — San Francisco, California
Low Grade Serous Carcinoma
View Study & Checklist ➔A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer
📍 Ironwood Cancer & Research Centers — Chandler, Arizona
Breast Cancer
View Study & Checklist ➔Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI)
📍 Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire
Breast Cancer
View Study & Checklist ➔Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease
📍 The Kirklin Clinic of UAB Hospital — Birmingham, Alabama
Breast Cancer
View Study & Checklist ➔Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies
📍 UCSF Medical Center at Mission Bay — San Francisco, California
Breast Cancer
View Study & Checklist ➔A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
📍 USO - Southern Cancer Center — Daphne, Alabama
Breast Neoplasms
View Study & Checklist ➔A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer
📍 Los Angeles Cancer Network — Los Angeles, California
Breast Cancer
View Study & Checklist ➔Letrozole in Uterine Leiomyosarcoma
📍 University of Colorado Cancer Center - Anschutz Cancer Pavilion — Aurora, Colorado
Uterine Leiomyosarcoma
View Study & Checklist ➔Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer
📍 Siteman Cancer Center at Washington University — St Louis, Missouri
Anatomic Stage III Breast Cancer AJCC v8
View Study & Checklist ➔Study of PF-07248144 in Advanced or Metastatic Solid Tumors
📍 HonorHealth — Scottsdale, Arizona
Locally Advanced or Metastatic ER+ HER2- Breast Cancer
View Study & Checklist ➔RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer
📍 Massachusetts General Hospital Cancer Center — Boston, Massachusetts
Endometrial Cancer
View Study & Checklist ➔A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors
📍 City of Hope — Duarte, California
HR+ Breast Cancer
View Study & Checklist ➔Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
📍 Clinical Trial Site — Hot Springs, Arkansas
Breast Cancer
View Study & Checklist ➔Phase IIIb Study of Ribociclib + ET in Early Breast Cancer
📍 Central Alabama Research — Birmingham, Alabama
Early Breast Cancer
View Study & Checklist ➔A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
📍 Southern Cancer Center, PC — Daphne, Alabama
Breast Cancer
View Study & Checklist ➔A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
📍 City of Hope - Phoenix — Goodyear, Arizona
Breast Cancer
View Study & Checklist ➔Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
📍 NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas
Anatomic Stage II Breast Cancer AJCC v8
View Study & Checklist ➔Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer
📍 UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California
Recurrent Endometrial Carcinoma
View Study & Checklist ➔Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib
📍 Parkland Hospital — Dallas, Texas
Breast Cancer
View Study & Checklist ➔Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer
📍 Yale New Haven Hospital — New Haven, Connecticut
Advanced HR+/HER2- Breast Cancer
View Study & Checklist ➔A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
📍 City of Hope Comprehensive Cancer Center — Duarte, California
Endometrial Cancer
View Study & Checklist ➔RADIANT: Pre-op Radiation With Abemaciclib and Letrozole
📍 RWJBarnabas Health Clara Maas Medical Center — Belleville, New Jersey
Breast Cancer
View Study & Checklist ➔Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy
📍 Yale University — New Haven, Connecticut
HER2 Negative Breast Cancer
View Study & Checklist ➔Prescription of Letrozole for Uterine Myoma
📍 University of California, Los Angeles — Los Angeles, California
Leiomyoma, Uterine
View Study & Checklist ➔Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial
📍 University of California at San Francisco — San Francisco, California
Infertility
View Study & Checklist ➔First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
📍 Ellison Clinic at Saint John's — Los Angeles, California
Breast Cancer
View Study & Checklist ➔DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
📍 Berkeley Outpatient Center — Berkeley, California
Ductal Carcinoma in Situ
View Study & Checklist ➔Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer
📍 Grady Healthcare System — Atlanta, Georgia
Anatomic Stage I Breast Cancer AJCC v8
View Study & Checklist ➔Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
📍 Emory University — Atlanta, Georgia
Advanced HR+/HER2- Breast Cancer
View Study & Checklist ➔A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
📍 Alaska Oncology and Hematology — Anchorage, Alaska
Breast Neoplasms
View Study & Checklist ➔A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
📍 HonorHealth — Phoenix, Arizona
Low Grade Serous Ovarian Cancer
View Study & Checklist ➔ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors
📍 Avenzo Therapeutics Recruiting Site — Los Angeles, California
HR+/HER2- Breast Cancer
View Study & Checklist ➔BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
📍 Sarah Cannon Research Institute (Scri) At Health One — Denver, Colorado
Advanced Solid Tumor
View Study & Checklist ➔A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)
📍 M D Anderson Cancer Center — Houston, Texas
Breast Cancer
View Study & Checklist ➔Study of Letrozole in Recurrent Gliomas
📍 University of Cincinnati — Cincinnati, Ohio
Brain Tumor
View Study & Checklist ➔BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease
📍 Alabama Oncology Princeton — Birmingham, Alabama
HR+/HER2- Breast Cancer
View Study & Checklist ➔Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer
📍 University of Alabama at Birmingham — Birmingham, Alabama
Locoregional Recurrence
View Study & Checklist ➔Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers
📍 University of Illinois Cancer Center — Chicago, Illinois
Breast Cancer
View Study & Checklist ➔Combined Immunotherapies in Metastatic ER+ Breast Cancer
📍 Weill Cornell Medicine — New York, New York
Breast Cancer
View Study & Checklist ➔Study of AVZO-021 in Patients With Advanced Solid Tumors
📍 Yale Cancer Center — New Haven, Connecticut
Advanced Solid Tumor
View Study & Checklist ➔ALPINE: Maintenance Letrozole/Abemaciclib
📍 Beth Israel Deaconess Medical Center — Boston, Massachusetts
Endometrial Cancer
View Study & Checklist ➔A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
📍 Research Site — Birmingham, Alabama
Breast Cancer, Early Breast Cancer
View Study & Checklist ➔A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
📍 Emory Winship Cancer Institute — Atlanta, Georgia
Low-Grade Serous Ovarian Cancer
View Study & Checklist ➔A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
📍 City of Hope — Duarte, California
Metastatic Breast Cancer
View Study & Checklist ➔A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
📍 Alaska Womens Cancer Care ( Site 0037) — Anchorage, Alaska
Malignant Neoplasm
View Study & Checklist ➔Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer
📍 Research Site — Gilbert, Arizona
Advanced Breast Cancer
View Study & Checklist ➔