80 Recruiting Studies Using Melphalan
Active clinical trials that use this intervention, sourced directly from the NIH registry.
Browse by conditionTrials Using Melphalan
A Phase I Study of Bendamustine and Melphalan Conditioning and Autologous Stem Cell Transplantation for Treatment of Multiple Myeloma and Relapsed/Refractory B-cell Lymphoma in Elderly Patients
π Memorial Sloan Kettering Cancer Center β New York, New York
Lymphoma
View Study & Checklist β2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy
π University of Arkansas for Medical Sciences β Little Rock, Arkansas
Multiple Myeloma
View Study & Checklist βAllogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
π Masonic Cancer Center, University of Minnesota β Minneapolis, Minnesota
SCID
View Study & Checklist βIbrutinib Before and After Stem Cell Transplant in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
π Anchorage Associates in Radiation Medicine β Anchorage, Alaska
Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type
View Study & Checklist βA Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant
π Memorial Sloan Kettering Cancer Center β New York, New York
Acute Myeloid Leukemia (AML)
View Study & Checklist β90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome
π City of Hope Medical Center β Duarte, California
Acute Lymphoblastic Leukemia
View Study & Checklist βGene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant
π UC San Diego Moores Cancer Center β La Jolla, California
HIV Infection
View Study & Checklist βClofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia
π City of Hope Medical Center β Duarte, California
Adult Acute Lymphoblastic Leukemia in Remission
View Study & Checklist βPeritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis
π Fred Hutch/University of Washington Cancer Consortium β Seattle, Washington
Primary Myelofibrosis
View Study & Checklist βTrial for Patients Not Qualifying for TT4 and TT5 Protocols Because of Prior Therapy
π University of Arkansas for Medical Sciences β Little Rock, Arkansas
Myeloma
View Study & Checklist βHLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
π City of Hope National Medical Center β Duarte, California
Acute Lymphoblastic Leukemia
View Study & Checklist βTocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation
π Weill Cornell Medical College β New York, New York
Hematologic Malignancy
View Study & Checklist βTCRΞ±Ξ²-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
π St. Jude Children's Research Hospital β Memphis, Tennessee
Acute Lymphoblastic Leukemia (ALL)
View Study & Checklist βTrial Evaluating MGTA-456 in Patients With High-Risk Malignancy
π Masonic Cancer Center at University of Minnesota β Minneapolis, Minnesota
Acute Myeloid Leukemia
View Study & Checklist βGiving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation
π Memorial Sloan Kettering Cancer Center β New York, New York
Hematologic Malignancies
View Study & Checklist βEarly Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
π Children's Hospital of Alabama β Birmingham, Alabama
Sickle Cell Disease
View Study & Checklist βChemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
π Roswell Park Cancer Institute β Buffalo, New York
Acute Myeloid Leukemia in Remission
View Study & Checklist βAn Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma
π Stanford Cancer Institute β Palo Alto, California
Metastatic Ocular Melanoma
View Study & Checklist βCombination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis
π City of Hope Medical Center β Duarte, California
Secondary Myelofibrosis
View Study & Checklist βMelphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
π Providence Hospital β Mobile, Alabama
Multiple Myeloma
View Study & Checklist βProvision of TCRΞ³Ξ΄ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in NaΓ―ve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
π St. Jude Children's Research Hospital β Memphis, Tennessee
Acute Lymphoblastic Leukemia (ALL)
View Study & Checklist βLenalidomide Plus Melphalan as a Preparative Regimen for Autologous Stem Cell Transplantation in Relapsed Multiple Myeloma: A Phase 1 / 2 Study
π Weill Cornell Medical College β New York, New York
Multiple Myeloma
View Study & Checklist βHLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis
π Mayo Clinic Arizona β Phoenix, Arizona
Acute Lymphoblastic Leukemia
View Study & Checklist βLenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant
π Mayo Clinic in Arizona β Scottsdale, Arizona
DS Stage I Multiple Myeloma
View Study & Checklist βAutologous Stem Cell Transplant for Neurologic Autoimmune Diseases
π Colorado Blood Cancer Institute β Denver, Colorado
Autoimmune Disease
View Study & Checklist βHelical Tomotherapy, Fludarabine Phosphate, and Melphalan Followed By Allo-HSCT in Hematological Malignancies
π City of Hope Medical Center β Duarte, California
Leukemia
View Study & Checklist βStudy of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.
π Memorial Sloan Kettering Cancer Center β New York, New York
Multiple Myeloma
View Study & Checklist βUARK 2008-02 A Trial for High-risk Myeloma Evaluating Accelerating and Sustaining Complete Remission
π University of Arkansas for Medical Sciences β Little Rock, Arkansas
Multiple Myeloma
View Study & Checklist βDaratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma
π City of Hope Medical Center β Duarte, California
Plasma Cell Myeloma
View Study & Checklist βReduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft
π Stanford University β Stanford, California
Allogeneic Hematopoietic Cell Transplantation (HCT)
View Study & Checklist βHigh Dose Therapy and Autologous Stem Cell Transplantation Followed by Infusion of Chimeric Antigen Receptor (CAR) Modified T-Cells Directed Against CD19+ B-Cells for Relapsed and Refractory Aggressive B Cell Non-Hodgkin Lymphoma
π Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) β Basking Ridge, New Jersey
Non-Hodgkin's Lymphoma
View Study & Checklist βMismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
π Children's Hospital of Alabama β Birmingham, Alabama
Acute Lymphoblastic Leukemia
View Study & Checklist βDetermination 2 - Isatuximab, Iberdomide, Bortezomib and Dexamethasone Induction, Followed by Risk- and Response-Adapted Consolidation and Maintenance Therapy, in Transplant-Eligible Patients With Newly Diagnosed Multiple Myeloma
π Beth Israel Deaconess Medical Center (BIDMC) β Boston, Massachusetts
Multiple Myeloma
View Study & Checklist βMMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma
π University of Arkansas for Medical Sciences β Little Rock, Arkansas
Multiple Myeloma (MM)
View Study & Checklist βA Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).
π Research Site β Tampa, Florida
Newly Diagnosed Multiple Myeloma (NDMM)
View Study & Checklist βCD34+ Transplants for Leukemia and Lymphoma
π Baptist Health South Florida/Miami Cancer Institute β Miami, Florida
Leukemia, Myeloid, Acute
View Study & Checklist βPhase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease
π Lucile Packard Children's Hospital β Palo Alto, California
Crohn Disease
View Study & Checklist βRisk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
π Chao Family Comprehensive Cancer Center, University of California Irvine β Orange, California
Allogeneic Hematopoietic Stem Cell Transplantation
View Study & Checklist βTCRΞ±Ξ²-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naΓ―ve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies
π St. Jude Children's Research Hospital β Memphis, Tennessee
Hematologic Malignancy
View Study & Checklist βThe Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
π City of Hope β Duarte, California
Peripheral Blood Stem Cell Transplantation
View Study & Checklist βPersonalized NK Cell Therapy in CBT
π M D Anderson Cancer Center β Houston, Texas
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
View Study & Checklist βTotal Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
π City of Hope Medical Center β Duarte, California
Acute Myeloid Leukemia With Complex Karyotype
View Study & Checklist βEmapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant
π City of Hope Medical Center β Duarte, California
Acute Myeloid Leukemia
View Study & Checklist βA Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant
π Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) β Basking Ridge, New Jersey
Multiple Myeloma
View Study & Checklist βReduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis
π Fred Hutch/University of Washington Cancer Consortium β Seattle, Washington
Primary Myelofibrosis
View Study & Checklist βMyeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma
π Masonic Cancer Center, University of Minnesota β Minneapolis, Minnesota
Neuroblastoma
View Study & Checklist βSHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
π Massachusetts General Hospital β Boston, Massachusetts
Pancreatic Adenocarcinoma Metastatic
View Study & Checklist βVedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning
π City of Hope Medical Center β Duarte, California
Acute Lymphoblastic Leukemia
View Study & Checklist βUmbilical Cord Blood Transplantation From Unrelated Donors
π Wilmot Cancer Institute β Rochester, New York
Acute Leukemia
View Study & Checklist βMT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma
π Masonic Cancer Center β Minneapolis, Minnesota
Autologous Stem Cell Transplant
View Study & Checklist βImmune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver
π Massachusetts General Hospital β Boston, Massachusetts
Uveal Melanoma
View Study & Checklist βPhase 2 Combination of Melphalan/HDS Via PHP + Tebentafusp in Treating Metastatic Uveal Melanoma
π Moffitt Cancer Center β Tampa, Florida
Metastatic Uveal Melanoma
View Study & Checklist βPersonalized Autologous Transplant for Multiple Myeloma
π Winship Cancer Institute of Emory University β Atlanta, Georgia
Multiple Myeloma
View Study & Checklist βMT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
π University of Minnesota Masonic Cancer Center β Minneapolis, Minnesota
Hematologic Malignancy
View Study & Checklist βTesting the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
π Children's Hospital of Alabama β Birmingham, Alabama
Ganglioneuroblastoma
View Study & Checklist βPre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma
π MD Anderson Cancer Center β Houston, Texas
Multiple Myeloma
View Study & Checklist βDinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
π Children's Hospital of Alabama β Birmingham, Alabama
Ganglioneuroblastoma, Nodular
View Study & Checklist βImpact of Recombinant Human Interleukin-7 (CYT107) on Tumor Clearance and Immune Reconstitution in Multiple Myeloma Patients After Autologous Hematopoietic Cell Transplant
π Washington University School of Medicine β St Louis, Missouri
Multiple Myeloma
View Study & Checklist βAlpha/Beta TCD HCT in Patients With Inherited BMF Disorders
π Masonic Cancer Center at University of Minnesota β Minneapolis, Minnesota
Fanconi Anemia
View Study & Checklist βProspective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors
π MD Anderson Cancer Center β Houston, Texas
Prospective Observational Study
View Study & Checklist βReduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
π UPMC Children's Hospital of Pittsburgh β Pittsburgh, Pennsylvania
Primary Immunodeficiency (PID)
View Study & Checklist βEvaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease
π City of Hope β Duarte, California
Refractory Metastatic Colorectal Cancer
View Study & Checklist βHepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
π UW Hospital and Clinics β Madison, Wisconsin
Metastatic Melanoma
View Study & Checklist βReduced Intensity Haploidentical BMT for High Risk Solid Tumors
π The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins β Baltimore, Maryland
Refractory and/or Relapsed Metastatic Solid Tumors
View Study & Checklist βTesting an Experimental Approach to Treat Patients With Plasma Cell Leukemia, The QUANTUM Trial
π Alliance for Clinical Trials in Oncology β Chicago, Illinois
Plasma Cell Leukemia
View Study & Checklist β225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
π City of Hope Medical Center β Duarte, California
Acute Lymphoblastic Leukemia
View Study & Checklist βAuto Stem Cell Transplant for Lymphoma Patients
π Masonic Cancer Center, University of Minnesota β Minneapolis, Minnesota
Non-Hodgkin Lymphoma
View Study & Checklist βIS-free Treg HaploHCT
π Dana Farber Cancer Institute β Boston, Massachusetts
Stem Cell Transplant Complications
View Study & Checklist βEarly Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
π Lucile Packard Children's Hospital β Palo Alto, California
SIOD
View Study & Checklist βRuxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes
π Fred Hutch/University of Washington Cancer Consortium β Seattle, Washington
Myelodysplastic/Myeloproliferative Neoplasm
View Study & Checklist βOrca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome
π City of Hope Medical Center β Duarte, California
Acute Lymphoblastic Leukemia
View Study & Checklist βMYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
π University of Alabama at Birmingham Cancer Center β Birmingham, Alabama
Acute Myeloid Leukemia
View Study & Checklist βBendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant
π M D Anderson Cancer Center β Houston, Texas
Hematopoietic and Lymphoid System Neoplasm
View Study & Checklist βPilot Study of Memory-like Natural Killer (ML NK) Cells After TCRΞ±Ξ² T Cell Depleted Haploidentical Transplant in AML
π Washington University School of Medicine β St Louis, Missouri
AML, Childhood
View Study & Checklist βA Study to Give Treatment Inside the Eye to Treat Retinoblastoma
π Children's Hospital of Alabama β Birmingham, Alabama
Bilateral Retinoblastoma
View Study & Checklist βRegenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures
π Johns Hopkins University β Baltimore, Maryland
Primary Immune Deficiency Disorder
View Study & Checklist βEvaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease
π Moffitt Cancer Center β Tampa, Florida
Metastatic Breast Cancer in the Liver
View Study & Checklist βAutologous Stem Cell Transplantation for Crohn's Disease
π UPMC Prebyterian- Adult Gastroenterology β Pittsburgh, Pennsylvania
Crohn's Disease
View Study & Checklist βCD45RA-depleted CD19-CAR T Cell Consolidation After TCRΞ±Ξ²+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma
π St. Jude Children's Research Hospital β Memphis, Tennessee
Relapsed Pediatric ALL
View Study & Checklist βComparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
π CTCA at Western Regional Medical Center β Goodyear, Arizona
AL Amyloidosis
View Study & Checklist β