40 Recruiting Studies Using Mesna

Active clinical trials that use this intervention, sourced directly from the NIH registry.

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Trials Using Mesna

🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

📍 Washington University School of Medicine — St Louis, Missouri

Soft Tissue Sarcoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma

📍 Arthur J.E. Child Comprehensive Cancer Centre — Calgary, Alberta

Lymphoma

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🔵 Active, Not Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies

📍 Masonic Cancer Center, University of Minnesota — Minneapolis, Minnesota

SCID

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

A Study of N9 Chemotherapy in Children With Neuroblastoma

📍 Memorial Sloan Kettering Cancer Center — New York, New York

Neuroblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

📍 The University of Texas MD Anderson Cancer Center — Houston, Texas

Melanoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

📍 National Institutes of Health Clinical Center — Bethesda, Maryland

Lymphoproliferative Disorders

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

📍 City of Hope National Medical Center — Duarte, California

Acute Lymphoblastic Leukemia

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Liver Transplantation With Tregs at MGH

📍 Massachusetts General Hospital: Transplantation — Boston, Massachusetts

Liver Transplant

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia (ALL)

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

📍 MD Anderson Cancer Center — Houston, Texas

Tumor

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia, in Relapse

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma

📍 MD Anderson Cancer Center — Houston, Texas

Lymphoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia (ALL)

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Paclitaxel, Ifosfamide and Cisplatin (TIP) Versus Bleomycin, Etoposide and Cisplatin (BEP) for Patients With Previously Untreated Intermediate- and Poor-risk Germ Cell Tumors

📍 University of Southern California — Los Angeles, California

Germ Cell Tumors

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Retinoblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

📍 Mayo Clinic Arizona — Phoenix, Arizona

Acute Lymphoblastic Leukemia

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

📍 Memorial Sloan Kettering Cancer Center Basking Ridge — Basking Ridge, New Jersey

Newly Diagnosed Ewing Sarcoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Hematologic Malignancy

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

📍 City of Hope — Duarte, California

Peripheral Blood Stem Cell Transplantation

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

📍 University of California, Davis Comprehensive Cancer Center — Sacramento, California

AML

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Pediatric Osteosarcoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Hematologic Malignancy

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

Umbilical Cord Blood Transplantation From Unrelated Donors

📍 Wilmot Cancer Institute — Rochester, New York

Acute Leukemia

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Stem Cell Transplantation in Crohn's Disease

📍 Cedars-Sinai Medical Center — Los Angeles, California

Crohn Disease

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

📍 Valkyrie Clinical Trials — Los Angeles, California

NHL

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

📍 Children's Hospital of Alabama — Birmingham, Alabama

Central Nervous System Nongerminomatous Germ Cell Tumor

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

📍 Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania

Systemic Sclerosis

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

📍 Alberta Children's Hospital — Calgary, Alberta

CNS Embryonal Tumor

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Pediatric Solid Tumor

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia, in Relapse

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

📍 St Jude Children's Research Hospital — Memphis, Tennessee

AML/MDS

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Acute Lymphoblastic Leukemia

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

IS-free Treg HaploHCT

📍 Dana Farber Cancer Institute — Boston, Massachusetts

Stem Cell Transplant Complications

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Haploidentical HCT for Severe Aplastic Anemia

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Aplastic Anemia

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Autologous Stem Cell Transplantation for Crohn's Disease

📍 UPMC Prebyterian- Adult Gastroenterology — Pittsburgh, Pennsylvania

Crohn's Disease

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

📍 St. Jude Children's Research Hospital — Memphis, Tennessee

Relapsed Pediatric ALL

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly

📍 MD Anderson Cancer Center — Houston, Texas

Splenomegaly

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

📍 National Institutes of Health Clinical Center — Bethesda, Maryland

Hematologic Neoplasms

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