100 Recruiting Studies Using Temozolomide

Active clinical trials that use this intervention, sourced directly from the NIH registry.

Browse by condition

Trials Using Temozolomide

🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

Locally Advanced Uterine Corpus Leiomyosarcoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.

📍 Col Uni Med Center New York Presby — New York, New York

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

📍 Holden Comprehensive Cancer Center — Iowa City, Iowa

Glioblastoma Multiforme

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

📍 University of California, San Francisco — San Francisco, California

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

📍 Children's Hospital of Alabama — Birmingham, Alabama

Anaplastic Astrocytoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

📍 University of Alabama at Birmingham — Birmingham, Alabama

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

📍 Mayo Clinic Hospital in Arizona — Phoenix, Arizona

Stage III Uterine Corpus Leiomyosarcoma AJCC v8

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

📍 Fairbanks Memorial Hospital — Fairbanks, Alaska

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors

📍 Phoenix Children's Hospital — Phoenix, Arizona

Solid Tumors

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab

📍 Duke University Medical Center — Durham, North Carolina

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

📍 Sibley Memorial Hospital — Washington D.C., District of Columbia

Glioblastoma Multiforme

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

Anaplastic Astrocytoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

📍 University of Alabama at Birmingham/Children's of Alabama — Birmingham, Alabama

Ewing Sarcoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

📍 Northwestern University — Chicago, Illinois

Glioblastoma

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

📍 Cohen Children's Medical Center of New York — New Hyde Park, New York

Pilomyxoid Astrocytoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine Carcinomas

📍 Kingman Regional Medical Center — Kingman, Arizona

Gastric Neuroendocrine Carcinoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

📍 Northwestern University — Chicago, Illinois

Astrocytoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

📍 Moffitt Cancer Center — Tampa, Florida

Recurrent Lung Small Cell Carcinoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

📍 Mayo Clinic Hospital in Arizona — Phoenix, Arizona

Glioblastoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH)

📍 Arizona Oncology Services Foundation — Phoenix, Arizona

Brain and Central Nervous System Tumors

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

📍 UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California

Advanced Malignant Solid Neoplasm

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🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)

📍 University of Florida Health — Gainesville, Florida

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma

📍 Department of Radiation Oncology at University of Iowa — Iowa City, Iowa

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

📍 City of Hope Medical Center — Duarte, California

Metastatic Leiomyosarcoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

📍 National Institutes of Health Clinical Center — Bethesda, Maryland

Gliosarcoma

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🔵 Active, Not Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

📍 Center for Neurosciences — Tucson, Arizona

Glioblastoma Multiforme of Brain

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

📍 Massachusetts General Hospital — Boston, Massachusetts

Glioblastoma

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

Study of Chemoimmunotherapy for High-Risk Neuroblastoma

📍 Memorial Sloan Kettering Cancer Center — New York, New York

Neuroblastoma (NB)

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

📍 Children's Hospital of Orange County - Orange — Orange, California

Glioma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

📍 Massachusetts General Hospital Cancer Center — Boston, Massachusetts

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)

📍 Banner Children's at Desert — Mesa, Arizona

Ganglioneuroblastoma, Nodular

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

rhIL-7-hyFc on Increasing Lymphocyte Counts in Patients With Newly Diagnosed Non-severe Lymphopenic Gliomas Following Radiation and Temozolomide

📍 Washington University School of Medicine — St Louis, Missouri

Glioma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma

📍 M D Anderson Cancer Center — Houston, Texas

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Nivolumab and Temozolomide Versus Temozolomide Alone in Newly Diagnosed Elderly Patients With GBM

📍 Duke University Medical Center — Durham, North Carolina

Glioblastoma Multiforme

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma

📍 Children's Hospital Los Angeles — Los Angeles, California

Recurrent Medulloblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

📍 Phoenix Children's Hospital — Phoenix, Arizona

Sarcoma, Ewing

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

📍 Children's Hospital of Alabama — Birmingham, Alabama

High Risk Neuroblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastoma

📍 University of Michigan Rogel Cancer Center — Ann Arbor, Michigan

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Testing the Addition of an Anticancer Drug, Olaparib, to the Usual Chemotherapy (Temozolomide) for Advanced Neuroendocrine Cancer

📍 Anchorage Associates in Radiation Medicine — Anchorage, Alaska

Advanced Adrenal Gland Pheochromocytoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)

📍 Mayo Clinic - Arizona — Phoenix, Arizona

Advanced or Metastatic NRAS-mutant Melanoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Study

📍 Mayo Clinic in Arizona — Scottsdale, Arizona

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Testing the Combination of Anti-Cancer Drugs Talazoparib and Temozolomide in Patients With Advanced Stage Rare Cancers, RARE 2 Trial

📍 National Cancer Institute Developmental Therapeutics Clinic — Bethesda, Maryland

Malignant Solid Neoplasm

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Comparing Capecitabine and Temozolomide in Combination to Lutetium Lu 177 Dotatate in Patients With Advanced Pancreatic Neuroendocrine Tumors

📍 Fairbanks Memorial Hospital — Fairbanks, Alaska

Metastatic Pancreatic Neuroendocrine Tumor

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

📍 Children's Hospital Los Angeles — Los Angeles, California

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Lonafarnib and Temozolomide in Treating Patients with Glioblastoma Multiforme That is Recurrent or Did Not Respond to Previous Treatment with Temozolomide

📍 M D Anderson Cancer Center — Houston, Texas

Malignant Supratentorial Neoplasm

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

📍 Mayo Clinic Hospital in Arizona — Phoenix, Arizona

Astrocytoma, IDH-Mutant, Grade 2

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

📍 City of Hope — Duarte, California

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma

📍 Memorial Sloan Kettering Cancer Center Basking Ridge — Basking Ridge, New Jersey

Newly Diagnosed Ewing Sarcoma

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70

📍 James Graham Brown Cancer Center — Louisville, Kentucky

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Dose Finding Study of [177Lu]Lu-NeoB in Newly Diagnosed Glioblastoma and in Recurrent Glioblastoma

📍 University of California LA — Los Angeles, California

Newly Diagnosed and Recurrent Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

📍 Augusta University, Georgia Cancer Center — Augusta, Georgia

Glioblastoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

📍 UAB Comprehensive Cancer Center — Birmingham, Alabama

Brain and Central Nervous System Tumors

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

📍 University of Alabama at Birmingham Cancer Center — Birmingham, Alabama

Adult Anaplastic Astrocytoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma

📍 Rady Children's Hospital — San Diego, California

Malignant Melanoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)

📍 Cedars-Sinai Medical Center — Los Angeles, California

Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer

📍 CBCC Global Research, Inc. at Comprehensive Blood and Cancer Center — Bakersfield, California

Recurrent Extensive Stage Small Cell Lung Carcinoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastoma

📍 Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center — Cleveland, Ohio

Glioblastoma

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastoma

📍 Mayo Clinic Hospital - Phoenix — Phoenix, Arizona

Glioblastoma

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

📍 University of California Los Angeles — Los Angeles, California

IDH1-mutant Glioma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastoma

📍 Stephenson Cancer Center, University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma

Glioblastoma

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🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma

📍 University of Pittsburgh Medical Center, Radiation Oncology — Pittsburgh, Pennsylvania

Glioblastoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

📍 University of Chicago Medical Center — Chicago, Illinois

Malignant Glioma of Brain

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors

📍 Kaiser Anaheim Medical Center — Anaheim, California

Gastrinoma

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🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic

Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme

📍 Barrow Neurological Institute (SJHMC) — Phoenix, Arizona

Glioblastoma

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🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

📍 UC San Diego Moores Cancer Center — San Diego, California

Primary Brain Tumor

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Mycophenolate Mofetil Combined With Radiation Therapy in Glioblastoma

📍 University of Michigan Rogel Cancer Center — Ann Arbor, Michigan

Recurrent Glioblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Surgical Pembro +/- Olaparib w TMZ for rGBM

📍 Massachusetts General Hospital — Boston, Massachusetts

Glioblastoma

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain Cancer

📍 Augusta University, Georgia Cancer Center — Augusta, Georgia

Progressive Pediatric Brain Cancer

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🟡 Not Yet Recruiting Phase3 💊 Investigational Drug / Biologic

PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma

📍 UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California

Glioblastoma

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🟡 Not Yet Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy

📍 Miami Herbert Wertheim Cancer Institute — Miami, Florida

Glioblastoma (GBM)

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🟡 Not Yet Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

NG101m Adjuvant Therapy in Glioblastoma Patients

📍 Yvonne Kew MD, PLLC — Houston, Texas

Glioblastoma Multiforme

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

Integrating Biology for Safe Intensification of Glioblastoma Hypofractionated Treatment on the MR-Linac

📍 NYU Langone Health — New York, New York

High-grade Glioma

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🟡 Not Yet Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Combination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)

📍 University of California, San Francisco — San Francisco, California

Glioblastoma

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Temozolomide, With or Without WSD0922-FU, for the Treatment of EGFR-Mutant, IDH-Wildtype Glioblastoma

📍 Mayo Clinic in Arizona — Scottsdale, Arizona

Glioblastoma, IDH-Wildtype

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🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic

Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC)

📍 Arthur J.E. Child Comprehensive Cancer Centre — Calgary, Alberta

Breast Cancer Triple Negative

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🟡 Not Yet Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

Comparison of Cerebraca Wafer Plus Temozolomide Versus Temozolomide Alone in Recurrent Glioblastoma

📍 Legorreta Cancer Center Warren Alpert Medical School of Brown University — Providence, Rhode Island

Recurrent Glioblastoma, IDH-Wildtype

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

📍 Children's Hospital Colorado — Aurora, Colorado

High Grade Glioma

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🟢 Recruiting Phase3 💊 Investigational Drug / Biologic

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

📍 Mayo Clinic Cancer Center — Phoenix, Arizona

Relapsed/Refractory Primary Central Nervous System Lymphoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

📍 University Of Colorado — Aurora, Colorado

Lymphoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

📍 Memorial Sloan Kettering Cancer Center — New York, New York

High-risk Neuroblastoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

📍 University of Alabama at Birmingham — Birmingham, Alabama

Glioblastoma, IDH-wildtype

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual Disease

📍 University of California, San Francisco — San Francisco, California

Medulloblastoma

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🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic

Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease

📍 Mayo Clinic in Rochester — Rochester, Minnesota

Glioma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

📍 Brigham and Women's Hospital — Boston, Massachusetts

Lymphoma

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🟢 Recruiting Phase3 💊 Investigational Drug / Biologic

SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

📍 Mayo Clinic — Phoenix, Arizona

Melanoma, Cutaneous Malignant

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

A Study of 177Lu-PSMA-617 in People With Gliomas

📍 Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) — Basking Ridge, New Jersey

Glioma

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

📍 Ohio State University Comprehensive Cancer Center — Columbus, Ohio

Clinical Stage IV Cutaneous Melanoma AJCC v8

View Study & Checklist ➔

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Pan Tumor Rollover Study

📍 Local Institution - 0220 — Huntsville, Alabama

Cancer

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

📍 Cedars-Sinai Medical Center — Los Angeles, California

Refractory Solid Tumors

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

📍 Northwestern University — Chicago, Illinois

Recurrent Glioblastoma, IDH-Wildtype

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

📍 Johns Hopkins Medical Institution — Baltimore, Maryland

Glioblastoma Multiforme

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)

📍 University of California, San Francisco — San Francisco, California

Glioblastoma

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

📍 John Hunter Children's Hospital — Newcastle, New South Wales

Childhood Cancer

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

📍 Augusta University, Georgia Cancer Center — Augusta, Georgia

Ependymoma

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🟢 Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

📍 University of Alabama at Birmingham — Birmingham, Alabama

Glioblastoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

📍 University of Alabama at Birmingham O'Neal Comprehensive Cancer Center — Birmingham, Alabama

Glioblastoma (GBM)

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🟢 Recruiting Phase3 💊 Investigational Drug / Biologic

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

📍 HonorHealth Scottsdale Osborn Medical Center — Scottsdale, Arizona

Glioblastoma

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

📍 OSF Saint Francis Medical Center — Peoria, Illinois

Small Cell Lung Cancer

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