S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer (NCT00070564)
🩺 Plain-English Summary (8th-Grade Level)
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and giving them after surgery may kill any remaining tumor cells. It is not yet known which combination chemotherapy regimen is more effective in treating resected breast cancer. PURPOSE: This randomized phase III trial is comparing 2 different regimens of combination chemotherapy to see how well they work in treating patients who have undergone surgery for stage I, stage II, or stage III breast cancer.
Who can join: Review the eligibility criteria below.
Location: Regional Medical Center — Anniston, Alabama
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (542 Sites)
- Regional Medical Center — Anniston, Alabama
- UAB Comprehensive Cancer Center — Birmingham, Alabama
- Providence Cancer Center at Providence Hospital — Mobile, Alabama
- Providence Cancer Center — Anchorage, Alaska
- Mayo Clinic Scottsdale — Scottsdale, Arizona
- Arizona Cancer Center at University of Arizona Health Sciences Center — Tucson, Arizona
- Hembree Mercy Cancer Center at St. Edward Mercy Medical Center — Fort Smith, Arkansas
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas
- Alta Bates Summit Comprehensive Cancer Center — Berkeley, California
- Peninsula Medical Center — Burlingame, California
- East Bay Radiation Oncology Center — Castro Valley, California
- Valley Medical Oncology Consultants - Castro Valley — Castro Valley, California
- Valley Medical Oncology — Fremont, California
- California Cancer Center - Woodward Park Office — Fresno, California
- Todd Cancer Institute at Long Beach Memorial Medical Center — Long Beach, California
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California
- Contra Costa Regional Medical Center — Martinez, California
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP — Marysville, California
- Memorial Medical Center — Modesto, California
- El Camino Hospital Cancer Center — Mountain View, California
- Sutter Health - Western Division Cancer Research Group — Novato, California
- Highland General Hospital — Oakland, California
- Alta Bates Summit Medical Center - Summit Campus — Oakland, California
- Bay Area Breast Surgeons, Incorporated — Oakland, California
- CCOP - Bay Area Tumor Institute — Oakland, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.