Who is eligible for clinical trial NCT01870752?

Participants must meet protocol criteria for Infertile Females or Females With Ovarian Insufficiency. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT01870752 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-09-04

Ovarian Tissue Transplantation (NCT01870752)

🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: Abramson Cancer Center at Penn Medicine

🩺 Plain-English Summary (8th-Grade Level)

Chemotherapy and radiation therapy for the treatment of cancer can compromise fertility. Ovarian tissue cryopreservation is an experimental strategy offered at The University of Pennsylvania to preserve future fertility (protocol 806062). The primary objective of this study is to determine the efficacy and safety of autologous transplantation of previously cryopreserved ovarian cortical tissue in patients who experience infertility or ovarian insufficiency after cancer treatments.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (6 items).

Location: Abramson Cancer Center of the University of Pennsylvania — Philadelphia, Pennsylvania

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Female patient between the ages of 18 and 45 years
Previously cryopreserved and stored cortical ovarian tissue available for autologous transplantation
Ovarian insufficiency defined as an elevated FSH over 10
Inability to conceive after 6 months of unprotected intercourse with male
Reasonably good health
Candidate for pregnancy
Written clearance for the procedure from the patients oncologist

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Patients considered to be high risk for surgical complications will be excluded from the research protocol
Women who are known to be positive for the BRCA mutation
Women with a history of leukemia, ovarian cancer or a cancer that likely involved the ovaries at the time of ovarian tissue collection
Women with psychological, psychiatric, or other conditions which prevent giving fully informed consent
Current pregnancy

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Abramson Cancer Center of the University of Pennsylvania — Philadelphia, Pennsylvania

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗