Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion (NCT03063892)
🩺 Plain-English Summary (8th-Grade Level)
Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (15 items).
Location: ProMedica Toledo Hospital — Toledo, Ohio
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Under the age of 60
- Does not sign consent or refuses participation
- Known hypersensitivity to tranexamic acid
- Multiple acute fractures
- Creatinine clearance \<30
- History of seizures
- Active hormone therapy
- History of coagulation abnormality
- History of deep vein thrombosis (DVT) or pulmonary embolism (PE) within the last year or history or recurrent DVT/PE
- Myocardial infarction (MI) and/or stents within the past year
- History of intracranial hemorrhage
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- ProMedica Toledo Hospital — Toledo, Ohio
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.