Effects of Blueberry on Gut Microbiota and Metabolic Syndrome (NCT03266055)
🩺 Plain-English Summary (8th-Grade Level)
There is growing evidence that nutritional intervention with dietary polyphenols can positively modulate the gut microbiota to improve cardiometabolic health. Whether the beneficial effects of blueberries on obesity and the metabolic syndrome can be linked to their potential impact on the gut microbiota and intestinal integrity remains speculative at this time. Moreover, the mechanisms of action underlying health benefits associated to blueberry consumption are still unknown. The investigators are thus proposing to combine the study of metagenomics, transcriptomics and metabolomics to test whether a prebiotic activity of highbush blueberries can play a role in the prevention of obesity-linked metabolic syndrome in a clinical setting.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (12 items).
Location: Laval University — Québec
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Metabolic disorders (hypertension, diabetes, hypercholesterolemia)
- Regular use of medication affecting study parameters
- Use of natural health product in the last 3 months
- Use of antibiotics in the last 3 months
- Nicotine users
- Allergy or intolerance for blueberries
- Blueberry taste aversion
- More than 2 alcohol drinks par day
- Particular dietary habits (vegetarism, gluten-free diet, cetogenic diet...)
- Weight change of more than 5% in the last 3 months
- Surgery in the last 3 months or planed during the study
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Laval University — Québec,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.