Who is eligible for clinical trial NCT03392181?

Participants must meet protocol criteria for Prostate Cancer. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT03392181 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-05-20

PET/MRI for the Staging of Newly Diagnosed Prostate Cancer (NCT03392181)

🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic Sponsor: Northwestern University

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to gain understanding of how PET-MR (positron emission tomography-magnetic resonance imaging) using the substance 18F-DCFPyL (PyL) may help in diagnosing prostate cancer and in determining the stage of prostate cancer before surgery.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (8 items).

Location: Northwestern University — Chicago, Illinois

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Patients must have a biopsy-proven diagnosis of high risk, very high risk, or locally advanced prostate cancer
Patients must have a diagnosis of high risk, very high risk, or locally advanced prostate cancer per NCCN Guidelines (T3-T4 disease)
Patients are healthy enough to be deemed surgical candidates with an ECOG performance status of 0-2
Patients must be age ≥ 18 years
Patients must agree to use adequate contraception (e.g. barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and for 30 days following completion of the imaging
Patients must have the ability to understand and the willingness to sign a written informed consent prior to registration on study

Usually NOT eligible if any of the following apply:

Exclusion Criteria
Patients who have contraindications to MRI (i.e. pacemakers, aneurysm clips or shaped fragments)
Patients who are claustrophobic will be required to take an anti-anxiety medication prescribed by their physician one hour prior to the scan
Patients may not be receiving any other treatments or investigational agents
Patients with a GFR \<30mL/min are ineligible to receive intravenous contrast per standard MR exclusion criteria
Patients not interested in pursuing surgical intervention for their disease (i.e. refusing treatment or requesting radiation oncology referral)
Patients who have received androgen deprivation therapy or prior surgery for prostate cancer
Patients who report taking multivitamins and/or folate supplements on the day of the scan

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Northwestern University — Chicago, Illinois

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗