Who is eligible for clinical trial NCT03972514?

Participants must meet protocol criteria for Brain Tumor. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT03972514 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-13

Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors. (NCT03972514)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Baptist Health South Florida

🩺 Plain-English Summary (8th-Grade Level)

This is a prospective, observational clinical trial investigating the morphological and volumetric changes in the brain following cranial Radiation Therapy in pediatric patients with brain or skull base tumors.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (5 items).

Location: Miami Cancer Institute at Baptist Health South Florida — Miami, Florida

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Patient (parent) must give study-specific informed consent on an IRB-approved consent prior to any research related procedures or study treatment. Written assent will be obtained as per Institutional guidelines.
Patients (Age equal to or less than 35 years old) that are planned to receive photon or proton RT to the brain according to standard of care are eligible to participate.
Patients that are planned to receive fractionated RT at 1.2-2.0 Gy RBE dose per fraction per standard of care are eligible to participate. If patients are planned to receive an alternative dose/fractionation regimen, then they should be treated according to standard of care and should not be enrolled.
Zubrod/Eastern Cooperative Oncology Group (ECOG) Performance Status ≤1

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Patient cannot undergo MRI without contrast as per standard of care
Patient and family do not speak English or Spanish
Patient receiving treatment with non-curative intent
Patients with an expected 3-year overall survival less than 50%

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Miami Cancer Institute at Baptist Health South Florida — Miami, Florida

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗