🏛️ Verified NIH Record • Updated 2026-08-03

Researching the Effect of Aerobic Exercise on Cancer (NCT03996239)

🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program Sponsor: Memorial Sloan Kettering Cancer Center

🩺 Plain-English Summary (8th-Grade Level)

This study is being done to answer the following question: Will aerobic exercise (exercise that stimulates and strengthens the heart and lungs, and improves the body's use of oxygen) change the biomarkers (signs of disease) found in the blood?

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (41 items) and avoid the listed exclusions (22 items).

Location: University of California, Los Angeles (Data or Specimen Analysis Only) — Los Angeles, California

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • Concurrent use of any form of antitumor therapy (endocrine therapy and anti-HER2 antibodies allowed)
  • Enrollment onto any other interventional investigational study except interventions determined by the PI not to confound study outcomes (does not apply to Cohort 5: EDD)
  • Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation.
  • Mental impairment leading to inability to cooperate
  • Any of the following contraindications to cardiopulmonary exercise testing (Cohorts 1 and 2 only):
  • Acute myocardial infarction within 3-5 days of any planned study procedures;
  • Unstable angina
  • Uncontrolled arrhythmia causing symptoms or hemodynamic compromise
  • Recurrent syncope
  • Active endocarditis
  • Acute myocarditis or pericarditis

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (10 Sites)

  • University of California, Los Angeles (Data or Specimen Analysis Only) — Los Angeles, California
  • SOMALOGIC (Data or Specimen Analysis Only) — Boulder, Colorado
  • Memorial Sloan Kettering Monmouth — Middletown, New Jersey
  • Memorial Sloan Kettering Bergen — Montvale, New Jersey
  • Memorial Sloan Kettering Commack — Commack, New York
  • Memorial Sloan Kettering Westchester — Harrison, New York
  • Memorial Sloan Kettering Cancer Center — New York, New York
  • Memorial Sloan Kettering Nassau — Uniondale, New York
  • LABORATORY CORPORATION OF AMERICA HOLDINGS (Data or Specimen Analysis Only) — Burlington, North Carolina
  • Duke University Medical Center (Data or Specimen Analysis Only) — Durham, North Carolina

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
🏛️ View Official NIH Record ↗