Who is eligible for clinical trial NCT04394637?

Participants must meet protocol criteria for Ventricular Arrhythmias. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04394637 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-06-03

Ultra High Resolution CT to Assess Role of Intramyocardial Fat and Delayed Enhancement in Ventricular Arrhythmogenesis (NCT04394637)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Johns Hopkins University

🩺 Plain-English Summary (8th-Grade Level)

This research is being done to determine how well cardiac computed tomography (CT) scanning measures of fat within the heart can predict abnormal heart rhythms and how well cardiac CT can measure scar within the heart versus cardiac magnetic resonance imaging (MRI). * People who have been enrolled in PROSe-ICD (NA\_00045142) and Reynolds (NA\_00037404) studies may join * The procedures, tests, drugs or devices that are part of this research and will be paid for by the study

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (5 items).

Location: Johns Hopkins Medical Institute — Baltimore, Maryland

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Patients aged 18 or older with history of ischemic cardiomyopathy enrolled in the current Reynolds study or PROSe-ICD study will be asked to participate
Women of child bearing potential must demonstrate a negative pregnancy test within 24 hours of the study CT
Ability to understand and willingness to sign the Informed Consent Form

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Known allergy to iodinated contrast media
Patients with glomerular filtration rate (GFR) ≤ 30 mL/min will not be enrolled in the study due to the use of intravenous iodinated contrast agents
Atrial fibrillation or uncontrolled tachyarrhythmia
Evidence of severe symptomatic heart failure (NYHA Class III or IV)

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Johns Hopkins Medical Institute — Baltimore, Maryland

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗