Oral Anti Diabetic Agents in the Hospital (NCT04416269)
🩺 Plain-English Summary (8th-Grade Level)
This randomized controlled clinical trial will assess whether continuation of home oral antidiabetic agents during hospitalization can be used as a safe and effective alternative to insulin therapy in the management of diabetes in the hospital. The primary outcome of the study is to determine differences in glycemic control as measured by mean daily blood glucose concentration between oral antidiabetic medications and basal bolus therapy in hospitalized patients with type 2 diabetes (T2D).
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (13 items).
Location: Emory University Hospital Midtown — Atlanta, Georgia
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- No known history of diabetes
- Laboratory evidence of diabetic ketoacidosis
- Subjects with a history of type 1 diabetes (suggested by BMI \< 25 requiring insulin therapy or with a history of diabetic ketoacidosis, or ketonuria)
- Meeting any exclusion criteria based on specific contraindications to their home oral therapy
- Acute critical illness or cardiac surgery expected to require admission to a critical care unit
- Gastrointestinal obstruction, adynamic ileus, or expected to require gastrointestinal suction
- Medical or surgical patients expected to be kept NPO for \>24-48 hours after admission or after completion of surgical procedure
- Impaired renal function (eGFR \<30 ml/min)
- Current treatment with oral or injectable corticosteroid
- Mental condition rendering the subject unable to understand the nature and scope of the study
- Female subjects who are pregnant or breastfeeding at time of enrollment in the study
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (3 Sites)
- Emory University Hospital Midtown — Atlanta, Georgia
- Emory University Hospital — Atlanta, Georgia
- Grady Memorial Hospital — Atlanta, Georgia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.