๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-10

Measuring Cell-Free DNA (cfDNA) Levels in People With Follicular Lymphoma (NCT04468841)

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ“‹ Clinical Research Protocol Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The researchers are doing this study to measure and test cell-free DNA (cfDNA) in the blood before, during, and after first-line treatment for follicular lymphoma. They will look at whether cfDNA levels are related to a person's response to the usual first-line treatment for follicular lymphoma. Researchers also want to understand how different genetic changes in follicular lymphoma relate to a person's response to the usual first-line treatment.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (2 items).

Location: Memorial Sloan Kettering Basking Ridge (All Protocol Activities) โ€” Basking Ridge, New Jersey

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • Patients receiving second or greater line of therapy (except in retrospective cohort of long-term survivors of FL \[i.e. \>10 years out from frontline treatment\])

๐Ÿ” Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

๐Ÿ“ All Participating Trial Locations (7 Sites)

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities) โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth (All protocol activities) โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen (All protocol Activities) โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Commack (All Protocol Activities) โ€” Commack, New York
  • Memorial Sloan Kettering Westchester (All Protocol Activities) โ€” Harrison, New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities) โ€” New York, New York
  • Memorial Sloan Kettering Nassau (All Protocol Activities) โ€” Uniondale, New York

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
๐Ÿ›๏ธ View Official NIH Record โ†—