A Study of Ixekizumab (LY2439821) in Children With Juvenile Idiopathic Arthritis Categories of Enthesitis-related Arthritis (Including Juvenile Onset Ankylosing Spondylitis) and Juvenile Psoriatic Arthritis (NCT04527380)
🩺 Plain-English Summary (8th-Grade Level)
The reason for this study is to see if the study drug ixekizumab is safe and effective in children with juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) (including juvenile onset ankylosing spondylitis \[JoAS\]) and juvenile psoriatic arthritis (JPsA).
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (6 items).
Location: Instituto CAICI SRL Loc. 15 — Rosario, Santa Fe Province
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Participants must not have active or history of inflammatory bowel disease
- Participants must not have active uveitis
- Participants must not have active or latent tuberculosis
- Participants must not have an active infection
- Participants must not have concurrent use of biologic agents for the treatment of the juvenile idiopathic arthritis
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (43 Sites)
- Instituto CAICI SRL Loc. 15 — Rosario, Santa Fe Province
- Centro Medico Privado de Reumatologia Loc. 20 — San Miguel de Tucumán, Tucumán Province
- Cliniques universitaires Saint-Luc — Brussels, Bruxelles-Capitale, Région de
- UZ Gent — Ghent, Oost-Vlaanderen
- UZ Leuven — Leuven, Vlaams-Brabant
- Oddeleni revmatologie deti a dospelych Loc. 1 — Prague, Praha 5
- Dětská klinika Loc. 11 — Olomouc,
- Klinika detskeho a dorostoveho lekarstvi Loc. 1 — Prague,
- Aarhus Universitetshospital, Skejby — Aarhus, Central Jutland
- Service rhumatologie Loc. — Bron, Auvergne-Rhône-Alpes
- Service de consultation pédiatrique Loc. 1 — Montpellier, Hérault
- Rhumatologie pediatrique et CEREMAIA Loc. 1 — Le Kremlin-Bicêtre, Paris
- RHUMATOLOGIE Loc. 1 — Poitiers, Vienne
- Centre d'Investigation Clinique Loc. 1 — Paris,
- Universitaetsklinikum Freiburg — Freiburg im Breisgau, Baden-Wurttemberg
- Asklepios Klinik Sankt Augustin — Sankt Augustin, North Rhine-Westphalia
- St. Josef-Stift Sendenhorst — Sendenhorst, North Rhine-Westphalia
- Helios Klinikum Berlin-Buch — Berlin,
- Charité Campus Virchow-Klinikum — Berlin,
- Klinikum Bremen-Mitte — Bremen,
- Praxis Kinder- und Jugendrheumatologie Dr. Ivan Foeldvari — Hamburg,
- University of Naples Federico II — Naples, Campania
- IRCCS Istituto Giannina Gaslini — Genoa, Liguria
- Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO — Milan, Lombardy
- Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico — Milan, Lombardy
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.