Who is eligible for clinical trial NCT04532424?

Participants must meet protocol criteria for Autism Spectrum Disorder. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04532424 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-08-16

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD (NCT04532424)

🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Stanford University

🩺 Plain-English Summary (8th-Grade Level)

Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (13 items).

Location: Stanford University — Stanford, California

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Diagnosis of Autism Spectrum Disorder (ASD)
Meet criteria for Autism Spectrum Disorder (ASD) on clinical assessments (ADOS-2 or CARS if conducted remotely \& ADI-R)
Aged between 12-45 years old
Have a reliable informant who can complete relevant questionnaires
Have DARB scores which indicate high levels (50% or above) of RRB on one of the following domains: Insistence on Sameness, Obsessive Compulsive Behaviors, and Unusual Interests

Usually NOT eligible if any of the following apply:

Exclusion criteria.
Any contraindications for TMS e.g. history of seizures other than clear substance-induced/fever-induced seizures with neurologist note or normal clean EEG and no seizure in at least 12 months prior to enrollment.
Pregnancy.
Any current or past history of any physical condition which in the investigator's opinion might put the subject at risk or interfere with study results interpretation.
Active substance use (\<1 week) or intoxication verified by toxicology screen--of cocaine, amphetamines, benzodiazepines.
Showing symptoms of withdrawal from alcohol or benzodiazepines.
DSM-5 diagnosis of bipolar disorder or a psychotic disorder e.g. schizophrenia.
Significant sensory impairments such as blindness or deafness.
Current severe insomnia (must sleep a minimum of 4 hours the night before stimulation).
Not willing to cooperate with the TMS procedures.
Currently taking Clozapine or another medication that the PI determines increases the risk of TMS or may disrupt the efficacy.
A motor threshold that is too high to allow safe/tolerable treatment.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Stanford University — Stanford, California

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗