Who is eligible for clinical trial NCT04584671?

Participants must meet protocol criteria for Covid19. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04584671 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-08-08

Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection (NCT04584671)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Western University, Canada

🩺 Plain-English Summary (8th-Grade Level)

This is a longitudinal study of the long-term impact of COVID-19 on the lungs. Participants will be followed over a period of up to 4 years and impacts of COVID-19 on the lungs will be measured with magnetic resonance imaging (MRI) using hyperpolarized xenon-129, pulmonary function tests, exercise capacity, computed tomography imaging and questionnaires.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (4 items).

Location: Department of Medicine (Respirology), McMaster University — Hamilton, Ontario

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Participants who are fluent in English reading, understanding and speaking
Written informed consent must be directly obtained from legally competent participants before any study-related assessment is performed.
Male and female participants ≥ 18 years and \< 80 years.
Participant experienced a documented case (documented by positive COVID-19 test and/or clinical history) of mild or severe COVID-19 infection.
Participants are within 3 months post-recovery.
100 participants will have had mild symptoms.
100 participants will have had severe symptoms, at least 50 of whom were hospitalized.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Participants meeting contraindications for undergoing an MRI such as participants with MRI-sensitive implants, tattoos with MRI-sensitive dye and severe claustrophobia.
Participant is, in the opinion of the Investigator, mentally or legally incapacitated, preventing informed consent from being obtained, or cannot read or understand written material.
Participant is unable to perform spirometry or plethysmography maneuvers.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Department of Medicine (Respirology), McMaster University — Hamilton, Ontario

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗