Who is eligible for clinical trial NCT04753996?

Participants must meet protocol criteria for Primary Sclerosing Cholangitis. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04753996 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-02-12

Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients (NCT04753996)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Mayo Clinic

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this research is to create a collection of bile, bile duct brushings and medical information from people with Primary Sclerosing Cholangitis (PSC) and controls to learn more about changes that occur in the liver.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (5 items).

Location: Mayo Clinic in Rochester — Rochester, Minnesota

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

PSC
Patients diagnosed with PSC between the age of 18 and 85.
The diagnosis of PSC will be based on standard PSC criteria including clinical and biochemical evidence of chronic cholestasis of at least six months duration, positive cholangiographic findings and compatible liver biopsies if available.
Women with PSC of childbearing potential and pregnant women will be offered enrollment because there is no risk to an unborn child in this investigation. Patients with PSC and Cholangiocarcinoma will be included. Controls
Controls without history of PSC or evidence of other chronic liver disease of either gender that will participate in this study should be between the ages of 18-85.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Patients unable to provide inform consent.
Prisoners and institutionalized individuals.
PSC with orthotopic liver transplantation
History of Roux En Y procedure

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Mayo Clinic in Rochester — Rochester, Minnesota

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗