Who is eligible for clinical trial NCT04908423?

Participants must meet protocol criteria for Stroke. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT04908423 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-11-19

Xeomin® and Gait Related Mobility After Stroke (NCT04908423)

🟢 Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Wake Forest University Health Sciences

🩺 Plain-English Summary (8th-Grade Level)

The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (8 items).

Location: Carolinas Rehabilitation — Charlotte, North Carolina

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Diagnosis of hemiparesis and spasticity secondary to stroke with upper and lower limb spasticity and unilateral motor and/or sensory deficit
No prior surgery to the lower limb
Able to walk at least 10 meters without physical assistance from another person and without an assistive device
Toe- ground clearance during swing phase without assistive device or orthoses
No treatment with botulinum toxin within the past 4 months

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Passive range of motion at either the ankle, knee, or elbow joint less than 30 degrees
Participants with uncorrected hearing impairment
Weight bearing restrictions due to concurrent orthopedic injuries that would make ambulating with or without an assistive device unsafe
Speech language expression deficit (e.g., aphasia)
Absence of proprioception upon neurologic examination
Presence of fixed contractures in the upper or lower extremities not correctable to neutral
Other confounding neurological diagnoses or active acute illness (cancer, Parkinson's disease, multiple sclerosis)

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Carolinas Rehabilitation — Charlotte, North Carolina

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗