🏛️ Verified NIH Record • Updated 2025-06-10

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer (NCT04952480)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: AHS Cancer Control Alberta

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to find out what effects of using adaptive radiotherapy to deliver chest radiation has on the ability to control lung cancer and side effects.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (10 items) and avoid the listed exclusions (19 items).

Location: Cross Cancer Institute — Edmonton, Alberta

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • No intrathoracic disease seen to target with radiation
  • Thoracic disease is contiguous to extra-thoracic sites, beyond ipsilateral supraclavicular lymph nodes
  • Mixed histology disease
  • Active serious infection requiring therapy
  • Brain metastasis that has not been symptomatically stable on dexamethasone
  • 4 or more sites of extrathoracic disease, even if 2 or more of these are present in the same organ system
  • Previous CNS or thoracic radiotherapy
  • Previous chemotherapy
  • Ineligibility for platinum doublet chemotherapy
  • Life expectancy of less than 3 months
  • Prior thoracic surgery

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

  • Cross Cancer Institute — Edmonton, Alberta

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
🏛️ View Official NIH Record ↗