Who is eligible for clinical trial NCT05035706?

Participants must meet protocol criteria for Acute Myeloid Leukemia. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT05035706 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-03-03

Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors (NCT05035706)

🔵 Active, Not Recruiting Early Phase1 🩺 Clinical Procedure Protocol Sponsor: M.D. Anderson Cancer Center

🩺 Plain-English Summary (8th-Grade Level)

This clinical trial assesses how the immune system responds to leukemia tumors after low dose radiation delivered as part of standard of care. The information learned in this study may help them know if adding immunotherapy (a type of treatment that uses the immune system to fight cancer) can be helpful in future leukemia patients receiving radiation.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (3 items).

Location: M D Anderson Cancer Center — Houston, Texas

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Patients diagnosed with new or recurrent myeloid leukemia
Aged \>= 18 years old
Eastern Cooperative Oncology Group (ECOG) performance status \< 4
Patient have measurable and amenable to biopsy under local anesthesia without the need for imaging directed procedure
Ability to understand and provide signed informed consent
Females must be surgically or biologically sterile or postmenopausal (amenorrhoeic for at least 12 months) or if of childbearing potential, must have a negative serum or urine pregnancy test within 72 hours before the start of the treatment. Women of childbearing potential must agree to use an adequate method of contraception during the study and until the last radiation treatment. Males must be surgically or biologically sterile or agree to use an adequate method of contraception during the study and until the last radiation treatment

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Patients who are unwilling to participate
Patients unwilling to undergo the biopsy before or after radiotherapy

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

M D Anderson Cancer Center — Houston, Texas

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗