Delirium Reduction With Ramelteon (NCT05069428)
🩺 Plain-English Summary (8th-Grade Level)
The overall purpose of this study is to identify a medication that might treat and/or prevent delirium in intensive care unit (ICU). Currently, there is no proven medical therapy for prevention or treatment of delirium. Ramelteon is a medication approved for insomnia. We hypothesize that ramelteon may help regulate the day/night cycle and decrease ICU delirium.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (12 items).
Location: Centennial Medical Center — Nashville, Tennessee
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Past medical history includes cirrhosis
- Active alcohol withdrawal
- Patients taking fluvoxamine prior to admission
- Self-reported hypersensitivity to ramelteon
- Incarcerated patients
- Pregnant patients
- Patients with acute neurological conditions including brain abscess, head bleed, meningitis
- Patients who are transferred from an outside hospital where they have resided for greater than 4 days
- Non-English speaking patients
- Hearing-impaired patients requiring sign language for communication
- Visually-impaired patients
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Centennial Medical Center — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.