🏛️ Verified NIH Record • Updated 2025-09-03
A Study to Evaluate White Matter Hyperintensities in Migraine (NCT05112289)
🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Mayo Clinic
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this research is to better understand brain white matter hyperintensities (WMH) in women with migraines
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (25 items).
Location: Mayo Clinic in Arizona — Phoenix, Arizona
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- History of SVI and/or history of MS or other neurological disease other than migraine.
- History of cancer or organ transplantation.
- Contraindication to MRI.
- Pregnancy.
- History of abnormal brain MRI other than WMH.
- Subjects not willing to comply with the study procedures will be removed from the study. Inclusion Criteria - SVI disease (n=10):
- Female only
- Ages \> 60 years.
- Presence of WMH on MRI. Exclusion Criteria:
- History of migraine and/or history of MS or other neurological disease other than SVI.
- History of cancer or organ transplantation.
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Mayo Clinic in Arizona — Phoenix, Arizona
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.