Who is eligible for clinical trial NCT05133102?

Participants must meet protocol criteria for Barrett Esophagus. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT05133102 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-05-08

Longitudinal Oral Microbiome Sampling for BE (NCT05133102)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Columbia University

🩺 Plain-English Summary (8th-Grade Level)

This is a longitudinal cohort study to assess the impact of repeated sampling of an oral microbiome signature for Barrett's esophagus (BE). Potential participants will be identified through chart review of patients who have had an endoscopy in the past three years.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (6 items).

Location: University of Michigan — Ann Arbor, Michigan

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Scheduled for an upper endoscopy or had upper endoscopy within past three years
Eighteen years of age or older
Capable of producing a saliva sample
Able to give informed consent
For BE patients only: Endoscopic evidence of Barrett's esophagus (at least 1 cm maximal BE length; i.e. Prague classification: any C, M≥1), and intestinal metaplasia present on esophageal biopsies

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
History of head and neck cancer or esophageal squamous cell or gastric cancer
History of esophageal or gastric surgery
Scheduled to undergo colonoscopy on the day of initial saliva collection
Scheduled only for Endoscopic retrograde cholangiopancreatography (ERCP) or Endoscopy ultrasound (EUS) without accompanying standard upper endoscopy on the day of initial saliva collection
For BE patients only: History of prior endoscopic therapy for BE except a history of prior Endoscopic mucosal resection (EMR) of focal lesions without subsequent ablative therapy is permitted

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (2 Sites)

University of Michigan — Ann Arbor, Michigan
Columbia University Irving Medical Center — New York, New York

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗