Who is eligible for clinical trial NCT05212428?

Participants must meet protocol criteria for Genetic Disorder. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT05212428 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-06-08

DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study (NCT05212428)

🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol Sponsor: Mayo Clinic

🩺 Plain-English Summary (8th-Grade Level)

This clinical trial collects information on how sequencing a patient's deoxyribonucleic acid (DNA) (i.e., the genetic material) could impact their health care. This study also develops and improves ways to include genomic information from DNA sequencing into the electronic health record to create a more complete "Health Tapestry" for each participant. Sequencing of a patient's DNA leads to the detection of genetic variants some of which determine risk for disease development. Discovery of those genetic variants in a patient could result in prevention, earlier diagnosis or better therapy of disease.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (8 items).

Location: Mayo Clinic in Arizona — Scottsdale, Arizona

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Age \>= 18 years
Registered Mayo Clinic patient
Able to provide informed written consent
E-mail and web access (for electronic consent, video education, registering with Helix and receiving results)
Ability to collect and ship saliva sample within the United States
Of note: Women, who are pregnant, or planning to become pregnant, can take part in this study. However, this study does not replace prenatal genetic testing. If participants have these concerns, they will be encouraged to contact their obstetrics (OB) provider or a genetic counselor to discuss further

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Other co-morbidity which would in physician's opinion interferes with patient's ability to participate in the study (eg: reduced ability to comprehend eg: dementia, intellectual disability, fluency in consent language)
Allogeneic bone marrow transplant (e.g. samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
Active hematological cancer or history of a hematological cancer
Resident of the state of New York
The Helix lab does not currently have New York state licensure
Residents without a shipping address in the United States
The Helix lab is unable to ship and receive samples internationally

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (3 Sites)

Mayo Clinic in Arizona — Scottsdale, Arizona
Mayo Clinic in Florida — Jacksonville, Florida
Mayo Clinic in Rochester — Rochester, Minnesota

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗