🏛️ Verified NIH Record • Updated 2026-06-12
Stimulation of the Larynx to Treat Unexplained Chronic Cough (NCT05273190)
🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: University of Minnesota
🩺 Plain-English Summary (8th-Grade Level)
Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (14 items).
Location: University of Minnesota — Minneapolis, Minnesota
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Electronic implants (e.g., pacemaker)
- Currently doing speech therapy for cough
- Contraindications to safe or effective VTS device use
- No regular access to wifi internet Neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis)
- Untreated carotid disease
- BMI \> 40 (for transmission of VTS through soft tissue)
- Current or recent (quit \< 3 months ago) smoking
- Known currently infectious cause for cough (e.g., TB, pertussis, COVID)
- History of known or suspected aspiration pneumonia
- Diagnosis or clinical suspicion of chronic obstructive pulmonary disease (COPD)
- Diagnosis or clinical suspicion of interstitial lung disease (ILD)
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- University of Minnesota — Minneapolis, Minnesota
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.