Exercise Training and Fat Metabolism in Postmenopausal Women (NCT05351476)
🩺 Plain-English Summary (8th-Grade Level)
Adipose tissue turnover plays a critical role in body weight maintenance, and obesity is underscored by the dysregulated balance between fat breakdown and synthesis. Although there are clear health-related benefits of physical activity, little is known about how resistance exercise, as opposed to endurance exercise, can reduce the risk of metabolic disorders, particularly in women. The goal of the proposed study is to investigate the effectiveness of resistance training to improve basal and stimulated fat metabolism in postmenopausal women with obesity and pre-diabetes, potentially serving as a viable and practical approach to prevent the onset of type 2 diabetes.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (10 items).
Location: Florida State University — Tallahassee, Florida
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Engaging in purposeful resistance training or endurance training (\> 20min/day, \> 2 days/week)
- Resting blood pressure above 140 mmHg systolic or 90 mmHg diastolic
- Type 1 or type 2 diabetes
- Medical problems in which exercise is contraindicated, such as chronic infections
- History of, or currently presentation with, cancer, cardiovascular or respiratory disease
- Uncontrolled thyroid dysfunction, liver or renal dysfunction
- Taking any medication affecting lipid metabolism
- Musculoskeletal disease or injury that would otherwise prevent engagement in resistance and endurance training
- Smokers and those with diagnosed eating disorders
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Florida State University — Tallahassee, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.