🏛️ Verified NIH Record • Updated 2026-06-22
Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure (NCT05690464)
🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Brigham and Women's Hospital
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to assess whether 480 mg/day magnesium glycinate supplementation for 12 weeks lowers blood pressure.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (16 items).
Location: Brigham and Women's Hospital — Boston, Massachusetts
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Measured seated diastolic blood pressure 100 mmHg or greater at screening visit
- Antacid or laxative use 4 times/week or more within the past 3 months
- History of cardiovascular disease (myocardial infarction, stroke, revascularization \[coronary artery bypass graft or percutaneous transluminal coronary angioplasty\], or angina pectoris)
- History of invasive cancer diagnosed within the last 5 years (non-melanoma skin cancer permitted)
- History of type 1 or 2 diabetes
- History of renal disease
- History of kidney failure
- History of dialysis
- History of pancreatitis
- History of inflammatory bowel disease
- History of hypermagnesemia
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Brigham and Women's Hospital — Boston, Massachusetts
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.