Trifecta-Lung cfDNA-MMDx Study (NCT05837663)
🩺 Plain-English Summary (8th-Grade Level)
Demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (1 items).
Location: St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT — Phoenix, Arizona
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria: Patients will be excluded from the study if they decline participation Are unable to give informed consent. Recipients of multiple organs, cancer patients and pregnant women
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (19 Sites)
- St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT — Phoenix, Arizona
- Division of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine — Gainesville, Florida
- Mayo Clinic Florida, 4500 San Pablo Rd — Jacksonville, Florida
- USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40 — Tampa, Florida
- Indiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L — Indianapolis, Indiana
- Johns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street — Baltimore, Maryland
- Division of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical Center — New York, New York
- The Ohio State University Wexner Medical Center, 410 W 10th Ave — Columbus, Ohio
- BAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth Street — Dallas, Texas
- UT Southwestern Medical Center, 5939 Harry Hines Blvd. — Dallas, Texas
- Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001 — Houston, Texas
- UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858 — San Antonio, Texas
- The Alfred Hospital, Monash University — Melbourne,
- Department of Thoracic Surgery, Medical University of Vienna — Vienna,
- Department of Medicine, University of Alberta — Edmonton, Alberta
- Alberta Transplant Applied Genomics Centre, University of Alberta — Edmonton, Alberta
- University Health Network, Toronto General Hospital — Toronto, Ontario
- Motol University Hospital, V Uvalu 84 — Prague,
- Charles University/Hospital Motol — Prague,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.