Who is eligible for clinical trial NCT05857618?

Participants must meet protocol criteria for Intraoperative Awareness. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT05857618 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-01-07

Study to Determine if Patients Exposed to General Anesthesia Significant Numbers of Times Would Increase the Risk for Intraoperative Awareness. (NCT05857618)

🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: University of Chicago

🩺 Plain-English Summary (8th-Grade Level)

This study will detect whether prior exposure to general anesthesia multiple times is associated with an increased incidence of awareness with explicit recall (AWR). This is especially important because patients who need to undergo multiple events of general anesthesia are medically some of the most vulnerable populations. The study hypothesizes that patients with significant exposure to general anesthesia have a higher incidence of AWR. This study may help clinicians and patients to better understand how to manage anesthesia care so that the safety and comfort of patients can be improved.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (3 items).

Location: University of Chicago Medical Center — Chicago, Illinois

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Patients who have been exposed to general anesthesia greater than 20 times or who have been exposed to general anesthesia 5 or fewer times between January 1, 1985 and June 15, 2017
Patients/their Guardians who consent to participate in the study.
Patients for whom a determination of AWR status can be made by anesthesiologists based on a standardized criteria.
Must be at least 7 years of age or older.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Healthy volunteers,
Patients who cannot recall whether or not they have experienced intraoperative awareness with explicit recall

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

University of Chicago Medical Center — Chicago, Illinois

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗