Who is eligible for clinical trial NCT06054295?

Participants must meet protocol criteria for Pediatric Central Nervous System Tumor. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06054295 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-12-11

Somatic Mosaicism in Twins Discordant for Childhood Cancer (NCT06054295)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Children's Oncology Group

🩺 Plain-English Summary (8th-Grade Level)

Somatic mosaicism in cancer associated genes is one potential explanation for discordance in childhood cancer that has not been fully explored to date. This pilot study will focus on twins with central nervous system (CNS) tumors who are identified through the Children's Oncology Group's Project: EveryChild (PEC) registry or volunteer.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (0 items).

Location: University of Minnesota — Minneapolis, Minnesota

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Newly diagnosed patient with CNS tumor or have recurrent disease and enrolled on APEC14B1.
Patient must have same sex twin. Note: (history of) treatment on a COG therapeutic trial is not required.
Patients must be diagnosed at \< 19 years of age at the time of diagnosis.
A family is eligible to participate if the twin with the CNS tumor is deceased but has a blood sample banked through APEC14B1.
All patients and/or their parents or legal guardians must provide informed consent. Assent will be obtained for participants between the ages of 8-17 years.
All institutional, FDA, and NCI requirements for human studies must be met.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

University of Minnesota — Minneapolis, Minnesota

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗