Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT) (NCT06071377)
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (5 items).
Location: University of Alabama — Birmingham, Alabama
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Unwilling to sign consent
- Known end-stage renal disease or dialysis
- Known SCD (including sickle cell-beta thalassemia)
- People who do not have SCT
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (10 Sites)
- University of Alabama — Birmingham, Alabama
- Loma Linda University Health Care — Loma Linda, California
- Nemours Children's Hospital — Wilmington, Delaware
- Indiana University — Indianapolis, Indiana
- Functional Fluidics — Detroit, Michigan
- University of North Carolina — Chapel Hill, North Carolina
- Duke University — Durham, North Carolina
- East Carolina University — Greenville, North Carolina
- Nationwide Children's Hospital — Columbus, Ohio
- UT Health Houston — Houston, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.