🏛️ Verified NIH Record • Updated 2026-06-03
A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam) (NCT06223360)
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Alzheimer's Disease Cooperative Study (ADCS)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine which may delay or slow the progression of the symptoms of early Alzheimer's disease.
Who can join: Review the eligibility criteria below.
Location: St. Joseph's Hospital and Medical Center/Barrow Neurological Institute — Phoenix, Arizona
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (47 Sites)
- St. Joseph's Hospital and Medical Center/Barrow Neurological Institute — Phoenix, Arizona
- Perseverance Research Center, LLC — Scottsdale, Arizona
- Banner Sun Health Research Institute — Sun City, Arizona
- The Neuron Clinic — Chula Vista, California
- University of California, Irvine — Irvine, California
- Pacific Research Network — Lemon Grove, California
- University of Southern California — Los Angeles, California
- Cedars Sinai, Los Angeles — Los Angeles, California
- Syrentis Clinical Research — Santa Ana, California
- JEM Research Institute — Atlantis, Florida
- Brain Matters Research — Delray Beach, Florida
- Neuropsychiatric Research Center of Southwest Florida — Fort Myers, Florida
- CCM Clinical Research Group, LLC — Miami, Florida
- Gonzalez MD & Aswad MD Health Services — Miami, Florida
- Miami Jewish Health — Miami, Florida
- Blue Medical Research Inc. — Miami, Florida
- Brainstorm Research — Miami, Florida
- Brain Matters Research (Kane Center) — Stuart, Florida
- Conquest Research — Winter Park, Florida
- Emory University Goizueta Alzheimer's Disease Research Center(GADRC) — Atlanta, Georgia
- Sandhill Research, LLC d/b/a Accel Research Sites — Decatur, Georgia
- Northwestern University Feinberg School of Medicine — Chicago, Illinois
- Rush University Medical Center — Chicago, Illinois
- Southern Illinois University — Springfield, Illinois
- University of Iowa — Iowa City, Iowa
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.