Who is eligible for clinical trial NCT06295744?

Participants must meet protocol criteria for Early-stage Breast Cancer. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06295744 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-23

Outcomes and Cosmesis With Whole Breast Irradiation and Boost (NCT06295744)

🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: University of Wisconsin, Madison

🩺 Plain-English Summary (8th-Grade Level)

This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integrated boost (SIB). 50 participants will be on study for up to 60 months.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (11 items).

Location: UW Carbone Cancer Center — Madison, Wisconsin

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Ability to understand and the willingness to sign a written informed consent document
Histologically confirmed early stage (stage T1-T2) invasive carcinoma of the breast or DCIS
Breast conserving surgery with negative margins and negative nodes (surgical axillary staging not mandatory), stage N0 or Nx
Treatment plan should include breast conserving surgery and adjuvant whole breast irradiation (WBI) therapy delivered with 3D-CRT or IMRT techniques
Treatment plan includes breast tumor bed boost
Willingness to comply with all study procedures and be available for the duration of the study

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Mastectomy of ipsilateral breast
Lack of histologic diagnosis
Histologic involvement of the axillary or regional nodes or metastatic disease
Accelerated partial breast irradiation treatment plan
Previous history of non-breast malignancy diagnosed in the past 5 years except for basal or squamous cell cancer of the skin
Previous history of chest radiation therapy
Previous history of ipsilateral breast cancer
Concurrent cytotoxic chemotherapy
Active connective tissue disease including scleroderma
Inability or unwillingness to return for required follow up visit

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

UW Carbone Cancer Center — Madison, Wisconsin

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗