Who is eligible for clinical trial NCT06355804?

Participants must meet protocol criteria for Multiple Sclerosis. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06355804 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2025-09-16

Lifestyle Physical Activity Intervention for Persons Newly Diagnosed With Multiple Sclerosis (NCT06355804)

🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program Sponsor: University of Illinois at Chicago

🩺 Plain-English Summary (8th-Grade Level)

The overall objective of the current study is to determine the efficacy of a 16-week remotely delivered lifestyle behavioral intervention compared with a control condition (i.e., waitlist control) in persons newly diagnosed with MS (disease duration ≤ 2 years). Specific Aim 1: To evaluate the changes in self-report and device-measured physical activity after the 16-week remotely delivered physical activity behavior change intervention compared with a control condition (i.e., waitlist control) in persons who have diagnosed with MS within the past two years. The investigators hypothesize that the 16-week behavior change intervention will yield greater improvements in physical activity levels than the control condition immediately after the intervention. Specific Aim 2: To investigate the efficacy of the 16-week, remotely delivered physical activity behavior change intervention compared with the control condition for improvements in fatigue, depression, anxiety, and QoL in persons newly diagnosed with MS. The investigators hypothesize that there will be beneficial effects on the symptoms and QoL outcomes immediately after the physical activity intervention compared with minimal changes in the control condition.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (9 items) and avoid the listed exclusions (3 items).

Location: University of Illinois Chicago — Chicago, Illinois

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

aged 18 years or older
self-reported diagnosis of MS by a neurologist within the past 2 years
relapse-free for the past 30 days
ability to speak and read English as primary language
internet and e-mail access, and willingness to complete the testing and questionnaires
ambulatory without an assistive device (e.g., cane)
insufficiently active (Godin Leisure-Time Exercise Questionnaire (GLTEQ) \< 14)
visual ability and literacy to read newsletter with font size 14 points
on a disease-modifying therapy.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
pregnant
have elevated risk for undertaking strenuous or maximal exercise based on two or more affirmatives on the Physical Activity Readiness Questionnaire (PAR-Q)

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

University of Illinois Chicago — Chicago, Illinois

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗