Who is eligible for clinical trial NCT06392126?

Participants must meet protocol criteria for Amyotrophic Lateral Sclerosis. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06392126 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-09

Personalized Antisense Oligonucleotide Therapy for A Single Participant With CHCHD10 ALS (NCT06392126)

🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: n-Lorem Foundation

🩺 Plain-English Summary (8th-Grade Level)

This research project entails delivery of a personalized antisense oligonucleotide (ASO) drug designed for a single participant with amyotrophic lateral sclerosis (ALS) due to a pathogenic variant in CHCHD10

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (3 items) and avoid the listed exclusions (3 items).

Location: Mayo Clinic — Jacksonville, Florida

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Informed consent/assent provided by the participant (when appropriate), and/or participant's parent(s) or legally authorized representative(s).
Ability to travel to the study site and adhere to study-related follow-up examinations and/or procedures and provide access to participant's medical records.
Genetically confirmed neurological disorder.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Participant has any condition that in the opinion of the Site Investigator, would ultimately prevent the completion of study procedures.
Use of an investigational medication within less than 5 half-lives of the drug at enrollment

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Mayo Clinic — Jacksonville, Florida

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗