Time-restricted Eating Among Pregnant Females With Severe Obesity (NCT06477120)
🩺 Plain-English Summary (8th-Grade Level)
In the United States, a body mass index (BMI) of at least 35.0 kg/m2 affects about 15% of women of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus, pre-eclampsia, premature birth, and at its most severe, fetal death, birth defects and a three-fold greater risk of maternal mortality. Observational studies suggest weight maintenance and even modest body fat loss and altering the maternal metabolic milieu (availability of glucose and lipids) in the gestational period may be important to reducing perinatal health risks among pregnant females with severe obesity. The proposed research aims to assess time-restricted eating in the 2nd and 3rd trimesters of pregnancy to explore the effects on maternal weight, and perinatal health outcomes compared to standard clinical care.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (9 items) and avoid the listed exclusions (14 items).
Location: University of Illinois at Chicago College of Applied Health Sciences — Chicago, Illinois
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion criteria:
- Deemed medically high risk
- Multiple pregnancy (e.g., twins)
- Type 1 or 2 diabetes mellitus
- Early gestational diabetes (diagnosed at \< = to17 weeks gestational age through an oral glucose tolerance test)
- Currently eating ≤ 12 hours daily
- Autoimmune disorder (e.g., rheumatoid arthritis)
- iron deficiency anemia
- Inflammatory bowel disease
- Previous spontaneous preterm birth
- History of bariatric surgery
- Night shift work
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- University of Illinois at Chicago College of Applied Health Sciences — Chicago, Illinois
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.