Who is eligible for clinical trial NCT06527157?

Participants must meet protocol criteria for Uterine Cancer. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06527157 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-08-13

Investigations of Reproductive Cancers in Women (NCT06527157)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: PinkDx, Inc.

🩺 Plain-English Summary (8th-Grade Level)

The goal of this study is to create a non-invasive diagnostic test to rule out gynecological cancer in females aged 45 and older with abnormal uterine or postmenopausal bleeding.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (9 items).

Location: University of Alabama, Birmingham — Birmingham, Alabama

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Evidence of a personally signed and dated informed consent form indicating that the subject has been informed of all pertinent aspects of the study.
Willing and able to comply with scheduled visits, study plan, and other procedures.
Expected to be available for the duration of the study and can be contacted by telephone during study participation.
Females aged 45 and older (with roughly 80% of enrolled subjects over the age of 50).
Presence of uterus.
AUB or PMB being worked up to diagnose the cause of the bleeding

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Investigator site staff members directly involved in the conduct of the study and their family members or subjects who are PinkDx, Inc. employees or their family members.
Other medical or psychiatric conditions that would increase the risk of study participation in the judgement of the Investigator.
Women who have had a hysterectomy.
Women with a known history of endometrial cancer or uterine sarcoma.
Women who have received prior treatment for endometrial cancer.
Inability or unwillingness to sign informed consent.
Clinical suspicion of pregnancy.
Women who have used a tampon within 7 days of sample collection.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (16 Sites)

University of Alabama, Birmingham — Birmingham, Alabama
Sutter Health — San Carlos, California
Advent Health Orlando — Orlando, Florida
Ob-Gyne Associates of Lake Forest, Ltd — Lake Forest, Illinois
Indiana University, Eskenazi Health — Indianapolis, Indiana
Mayo Clinic — Rochester, Minnesota
Washington University School of Medicine — St Louis, Missouri
Columbia University — New York, New York
Summa Health — Akron, Ohio
The Ohio State University — Columbus, Ohio
Avera Research Institute — Sioux Falls, South Dakota
University of Tennessee Health Science Center — Memphis, Tennessee
Meharry Medical College — Nashville, Tennessee
Baylor College of Medicine/Texas Children's Hospital — Houston, Texas
Houston Methodist — Houston, Texas
University of Texas Health Science Center at San Antonio — San Antonio, Texas

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗