Who is eligible for clinical trial NCT06593093?

Participants must meet protocol criteria for Opioid Use Disorder. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06593093 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-02-19

A Bundled Intervention (NCT06593093)

🟢 Recruiting Phase1 / Phase2 📋 Clinical Research Protocol Sponsor: University of Alabama at Birmingham

🩺 Plain-English Summary (8th-Grade Level)

Opioid overdose deaths have reached historically high records in the United States and are particularly concentrated among patients after emergency department (ED) discharge. Evidence-based treatment modules to reduce repeat opioid overdose and mortality are lacking in this patient population. A bundled intervention is proposed, including telehealth, peer support specialist, buprenorphine, and linkage for definitive care, that is designed to increase treatment uptake in this patient population post-ED discharge, reduce repeat opioid overdoses, and end overdose deaths.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (8 items).

Location: UAB — Birmingham, Alabama

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

discharged from the ED and inpatient settings at the UAB hospital
19 years or older (the age of majority in Alabama);
diagnosis of OUD and experiencing opioid overdose in the last 12 months;
prescribed buprenorphine in the ED and willing to continue buprenorphine post-ED discharge;
English speaking;
not actively psychotic and suicidal, or cognitively impaired.
Patients who are admitted to the hospital from the ED will be eligible for enrollment.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
living in a restricted environment (e.g., prison or jail facility, etc.);
currently enrolled in other clinical studies;
anticipated to take other prescribed opioids except buprenorphine for a medical condition longer than three months;
known allergic reaction to buprenorphine;
critically ill or injured;
females with pregnancy (they are anticipated to request a higher level of care).
living outside of Alabama

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

UAB — Birmingham, Alabama

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗