Who is eligible for clinical trial NCT06721390?

Participants must meet protocol criteria for Aging. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06721390 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-06-11

Music Improvisation Training on Cognitive Function in Older Adults (NCT06721390)

🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program Sponsor: University of California, San Francisco

🩺 Plain-English Summary (8th-Grade Level)

This project will study the effects and mechanisms of a music improvisation training intervention on self-regulation of older adults with and without MCI. The investigator's overall hypothesis is that improvisation training will lead to improvements in self-regulation, compared to controls, and that improvisation training will be associated with specific changes in prefrontal brain networks and ultimately cognitive engagement.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (8 items).

Location: The study is taking place at community sites in San Francisco. — San Francisco, California

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Age 60 and over
Living independently in the community
Sufficient visual and hearing acuity (age-related to normal hearing loss, with assistive devices)
Less than three years of formal music training (as indicated by private music lessons does not include group or ensemble classes) and not currently reading or engaging in music performance
English fluency rated fairly well to well
MoCA score of 22-30 or diagnosis of "mild cognitive impairment
Not currently taking psychoactive medications, antidepressants, or sleep medications that could adversely affect cognitive abilities.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Medical diagnosis of dementia (any etiology)
Inability to move the hands or use all 10 digits (extensive arthritis, neuropathy, missing digits)
Score \< 22 on MoCA
Current (but not prior) severe psychiatric disorder, serious medical condition (e.g., stroke, TIA) that would interfere with participation in the study
Poor English fluency
Musician or previously trained in jazz improvisation, more than three years of formal music instruction or training and/or currently engaged in musical performance
Plans to move out of the area within six months

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

The study is taking place at community sites in San Francisco. — San Francisco, California

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗