Who is eligible for clinical trial NCT06749262?

Participants must meet protocol criteria for Chronic Obstructive Pulmonary Disease. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06749262 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-04-07

Inclined Versus Standard Exercise for COPD Patients (NCT06749262)

🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: VA Office of Research and Development

🩺 Plain-English Summary (8th-Grade Level)

This study is designed to provide information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation is an exercise program for COPD patients that is recommended and benefits some, but not all, patients. The question being studied in this trial is whether during an exercise program, walking on an incline might be better than walking on faster on a flat surface in training muscles so that patients might be less short of breath with exercise.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (7 items) and avoid the listed exclusions (5 items).

Location: Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE — Omaha, Nebraska

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Veterans from all sex/gender, race, and ethnicity will be recruited
All subjects will undergo post-bronchodilator spirometry and be clinically stable
All subjects must have documented FEV1/FVC ratio of \<0.7, and between 30% to 80% FEV1% predicted
If subjects have non-qualifying spirometry, they will not be screened further
Subjects with qualifying spirometry will be screened further
Potential subjects must have a BMI of less than 35 kg/m2 and must be free from co-morbidities that may affect walking patterns
e.g., peripheral arterial disease, diabetes, low back pain

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Confounding effects such as neurological, musculoskeletal, or metabolic disease
Subjects taking medications that alter mood or metabolic demand will be excluded
All potential subjects must be cleared for participation by a physician after undergoing a cardiopulmonary exercise test
Require an O2 mask during rest or activity

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE — Omaha, Nebraska

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗