🏛️ Verified NIH Record • Updated 2026-05-27

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE (NCT06777368)

🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Medtronic Cardiovascular

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo Transcatheter Aortic Valve Replacement (TAVR).

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (1 items) and avoid the listed exclusions (7 items).

Location: University of Alabama at Birmingham — Birmingham, Alabama

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion Criteria:
  • BVF due solely to paravalvular regurgitation
  • Active endocarditis
  • Untreated acute valve thrombosis
  • Life-expectancy less than 1-year
  • Subject is less than legal age of consent, legally incompetent, or otherwise vulnerable
  • Participating in another study that may influence the outcome of this study

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (71 Sites)

  • University of Alabama at Birmingham — Birmingham, Alabama
  • Abrazo Arizona Heart Hospital — Phoenix, Arizona
  • Tucson Medical Center — Tucson, Arizona
  • Kaiser Permanente Los Angeles Medical Center — Los Angeles, California
  • Sutter Heatlh — Sacramento, California
  • Kaiser Permanente Northern California — Sacramento, California
  • Stanford Hospital & Clinics — Stanford, California
  • Los Robles Regional Medical Center — Thousand Oaks, California
  • Medical Center of the Rockies — Loveland, Colorado
  • Hartford Hospital — Hartford, Connecticut
  • Yale New Haven Hospital — New Haven, Connecticut
  • MedStar Washington Medical Center — Washington D.C., District of Columbia
  • Morton Plant Hospital — Clearwater, Florida
  • HealthPark Medical Center, Lee Memorial Health — Fort Myers, Florida
  • Orlando Health/Orlando Regional Medical Center — Orlando, Florida
  • Tampa General/USF — Tampa, Florida
  • Parkview Health — Fort Wayne, Indiana
  • Saint Vincent Heart Center of Indiana — Indianapolis, Indiana
  • MercyOne Iowa Heart Center — Des Moines, Iowa
  • University of Iowa Hospitals and Clinics — Iowa City, Iowa
  • The University of Kansas — Kansas City, Kansas
  • Ascension Via Christi St. Francis — Wichita, Kansas
  • Maine Medical Center — Portland, Maine
  • Medstar Union Memorial Hospital — Baltimore, Maryland
  • The Johns Hopkins Hospital — Baltimore, Maryland

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
🏛️ View Official NIH Record ↗