Who is eligible for clinical trial NCT06846515?

Participants must meet protocol criteria for Gout. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06846515 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-08-31

Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301) (NCT06846515)

ACTIVE_NOT_RECRUITING Phase3 💊 Investigational Drug / Biologic Sponsor: Arthrosi Therapeutics

🩺 Plain-English Summary (8th-Grade Level)

This study will assess the serum uric acid lowering effect and safety of AR882 in gout patients at two doses compared to placebo over 12 months

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (6 items) and avoid the listed exclusions (3 items).

Location: Arthrosi Investigative Site (620) — Birmingham, Alabama

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

History of gout
Occurrence of ≥ 2 self-reported gout flares in the last 12 months
Body weight no less than 50 kg
Patients who are NOT on approved urate-lowering therapy (ULT) must have sUA ≥ 7 mg/dL
Patients who are on medically appropriate ULT must have sUA \> 6 mg/dL
Serum creatinine must be \< 3.0 mg/dL and estimated CLcr ≥ 30 mL/min

Usually NOT eligible if any of the following apply:

Malignancy within 5 years, except for successfully treated basal or squamous cell carcinoma of the skin
Pregnant or breastfeeding
History of symptomatic kidney stones within the past 6 months

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (83 Sites)

Arthrosi Investigative Site (620) — Birmingham, Alabama
Arthrosi Investigative Site (616) — Huntsville, Alabama
Arthrosi Investigative Site (680) — Peoria, Arizona
Arthrosi Investigative Site (640) — Phoenix, Arizona
Arthrosi Investigative Site (617) — Little Rock, Arkansas
Arthrosi Investigative Site (614) — Garden Grove, California
Arthrosi Investigative Site (618) — La Mesa, California
Arthrosi Investigative Site (687) — La Mesa, California
Arthrosi Investigative Site (655) — La Palma, California
Arthrosi Investigative Site (632) — Lincoln, California
Arthrosi Investigative Site (605) — Lomita, California
Arthrosi Investigative Site (675) — Long Beach, California
Arthrosi Investigative Site (603) — Santa Monica, California
Arthrosi Investigative Site (672) — Tarzana, California
Arthrosi Investigative Site (656) — Thousand Oaks, California
Arthrosi Investigative Site (660) — Aurora, Colorado
Arthrosi Investigative Site (669) — Colorado Springs, Colorado
Arthrosi Investigative Site (612) — Fort Collins, Colorado
Arthrosi Investigative Site (665) — Cooper City, Florida
Arthrosi Investigative Site (613) — Jupiter, Florida
Arthrosi Investigative Site (611) — Miami, Florida
Arthrosi Investigative Site (644) — Miami, Florida
Arthrosi Investigative Site (694) — Palmetto Bay, Florida
Arthrosi Investigative Site (615) — Sanford, Florida
Arthrosi Investigative Site (600) — Tampa, Florida

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗