🏛️ Verified NIH Record • Updated 2026-07-28
Pelacarsen Roll-over Extension Program (NCT06875973)
🟢 Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals
🩺 Plain-English Summary (8th-Grade Level)
This non-randomized, rollover extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed either of the double-blind parent studies (CTQJ230A12303 or CTQJ230A12304).
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (2 items) and avoid the listed exclusions (5 items).
Location: Parkway Medical Center — Birmingham, Alabama
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Participants who permanently discontinued the study treatment as mandated per protocol or due to adverse events in the parent study
- Any medical condition(s) in the investigator's opinion that may put the participant at risk or interfere with the study participation
- Participants who are receiving another investigational drug or device before the open-label treatment period
- Participants who have a known sensitivity to the study drug and are deemed as unsuited for the study by the investigator Other protocol-defined inclusion/exclusion criteria may apply.
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (97 Sites)
- Parkway Medical Center — Birmingham, Alabama
- Cardiology and Medicine Clinic PA — Little Rock, Arkansas
- National Heart Institute — Beverly Hills, California
- Hope Clinical Research — Canoga Park, California
- Valley Clinical Trials Inc — Covina, California
- NICRs Research Center — Garden Grove, California
- University of Calif Irvine Med Cntr — Irvine, California
- Long Beach Clinical Trials — Long Beach, California
- Angel City Research Inc — Los Angeles, California
- California Medical Research Associates Inc — Northridge, California
- Stanford Health Care — Stanford, California
- Excel Medical Clinical Trials LLC — Boca Raton, Florida
- C and A Clinical Trials — Cape Coral, Florida
- Proactive Clinical Research — Fort Lauderdale, Florida
- Proactive Clinical Research — Fort Lauderdale, Florida
- National Research Institute — Hialeah, Florida
- Sister Life Research Inc — Hialeah, Florida
- Zenith Clinical Research — Hollywood, Florida
- Columbus Clinical Services LLC — Miami, Florida
- Finlay Medical Research — Miami, Florida
- Infinite Clinical Research — Miami, Florida
- International Research Associates LLC — Miami, Florida
- Baptist Health South — Miami, Florida
- A&A Research Group Inc — Miami, Florida
- Inpatient Research Clinical LLC — Miami Lakes, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.