Who is eligible for clinical trial NCT06989099?

Participants must meet protocol criteria for Lymphedema. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06989099 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-02-17

Lymphedema Prevention Through Immediate Lymphatic Reconstruction (LILY) Trial. (NCT06989099)

🟢 Recruiting Phase2 🩺 Clinical Procedure Protocol Sponsor: M.D. Anderson Cancer Center

🩺 Plain-English Summary (8th-Grade Level)

To learn if reconstruction of the lymphatic system at the time of axillary lymphadenectomy can reduce the risk of developing lymphedema.

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (5 items) and avoid the listed exclusions (9 items).

Location: MD Anderson Cancer Center — Houston, Texas

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Participants diagnosed with IBC.
Participants who have been scheduled for ILR/pLVB by their treating physician/surgeon at the time of their axillary lymphadenectomy for breast cancer
Participants willing and able to comply with the study protocol requirements and all study-related visit requirements.
Female subjects at least 18 years old and capable of providing consent to participate.
Females of childbearing potential must have a negative urine pregnancy test within 36 hours prior to study drug administration and agree to use a medically accepted method of contraception for a period of one month following the study.

Usually NOT eligible if any of the following apply:

Exclusion Criteria:
Patients known to be pregnant or breast-feeding.
Patients with known or suspected iodine or ICG hypersensitivity.
Patients unable to remain stationary for one hour.
Active cellulitis.
Subjects with a preoperative clinical lymphedema diagnosis.
Subjects undergoing bilateral ALND.
Subjects requiring immediate chest wall reconstruction with a pedicled or microvascular flap, or those that have received preoperative radiation therapy.
Patients with BMI \>45kg/m2.

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

MD Anderson Cancer Center — Houston, Texas

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

🏛️ View Official NIH Record ↗