🏛️ Verified NIH Record • Updated 2026-05-25

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) (NCT06991257)

🟢 Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Pfizer

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to learn about the safety and effects of the study medicine (PF-07328948) for the possible treatment of heart failure (HF).

Who can join: Review the eligibility criteria below.

Location: National Heart Institute — Beverly Hills, California

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (142 Sites)

  • National Heart Institute — Beverly Hills, California
  • Orange County Research Center — Lake Forest, California
  • Comprehensive Cardiovascular Care — Santa Maria, California
  • FOMAT Medical Research — Santa Maria, California
  • FWD Clinical Research — Boca Raton, Florida
  • Jacksonville Center for Clinical Research — Jacksonville, Florida
  • Infinite Clinical Research — Miami, Florida
  • Flourish Research Acquisition, LLC dba Flourish Research - North Miami — Miami, Florida
  • Amavita Research Services — North Miami Beach, Florida
  • Clinical Site Partners, LLC dba Flourish Research — Winter Park, Florida
  • NMH Clinical Research Unit — Chicago, Illinois
  • Northwestern Memorial HealthCare - Arkes Pavilion — Chicago, Illinois
  • Northwestern Memorial HealthCare - Feinberg Pavilion — Chicago, Illinois
  • Northwestern Memorial HealthCare - Galter Pavilion — Chicago, Illinois
  • Northwestern Memorial Hospital Investigational Drug Service (IDS) — Chicago, Illinois
  • Northwestern University — Evanston, Illinois
  • Chicago Medical Research — Hazel Crest, Illinois
  • NexGen Research — Fort Wayne, Indiana
  • Reid Physician Associates — Richmond, Indiana
  • Ascension Saint Agnes Heart Care — Baltimore, Maryland
  • Chesapeake Cardiac Care — Bowie, Maryland
  • Flourish Research - Bowie — Bowie, Maryland
  • Velocity Clinical Research, Lincoln, Pioneer Heart Institute — Lincoln, Nebraska
  • NexGen Research — Lima, Ohio
  • Headlands Horizons, LLC dba Headlands Research-Brownsville — Brownsville, Texas

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
🏛️ View Official NIH Record ↗