🏛️ Verified NIH Record • Updated 2025-11-13
Ischemic Preconditioning in Osteoarthritis and Back Pain (NCT07003113)
🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: University of Illinois at Chicago
🩺 Plain-English Summary (8th-Grade Level)
We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in individuals with knee osteoarthritis and low back pain.
Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (11 items).
Location: Human and Sport Performance Lab — Chicago, Illinois
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistCheck every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).
Usually NOT eligible if any of the following apply:
- Exclusion Criteria:
- Younger than 50 years old
- History of Knee or Hip Replacements
- History of steroid injection within the previous 6 months
- Presence of neuromuscular joint condition that affects lower extremity function
- History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
- History of heart failure or thrombosis
- Allergic to ultrasound gel
- History of spine surgery
- Non-English speaker
- Currently pregnant or intends to become pregnant during the study
🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.
📍 All Participating Trial Locations (1 Sites)
- Human and Sport Performance Lab — Chicago, Illinois
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.