Family Communications After Genetic Testing (NCT07143487)

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

1. STEP 1 PROBANDS: Age \>= 18 years
2. STEP 1 PROBANDS: Patients with a newly diagnosed (within 3 months of registration), primary colorectal adenocarcinoma, stage I to IV
3. Histologically proven stage I to IV colon or rectal adenocarcinoma (any T or N, M+). Tumors deemed to originate in the colon can extend into/involve the small bowel (e.g., those at the ileocecal valve). Tumors will be regarded as originating in the colon if the entire tumor is in the colon. In the case of rectal involvement, the cancer will be considered a rectal primary
4. Patients with more than one primary colon adenocarcinoma are eligible
5. STEP 1 PROBANDS: No patients with stage 0 or in-situ colorectal cancer
6. STEP 1 PROBANDS: Patients who have had prior malignancies are eligible, including non-invasive cancers
7. STEP 1 PROBANDS: Patients with synchronous second malignancies are eligible
8. STEP 1 PROBANDS: Have not received germline testing in the 2 years prior to enrollment or known hereditary colon cancer syndromes
9. STEP 1 PROBANDS: Patients must have at least 2 living FDRs who meet the eligibility criteria, with whom the patient is willing to share their cancer diagnosis
10. STEP 1 PROBANDS: In order to complete the mandatory patient-completed measures and view the video and receive genetic education and counseling, participants must be able to speak and read English or Spanish
11. STEP 1 PROBANDS: No known diagnosis of dementia or cognitive impairment. Persons with impaired decision-making capacity are ineligible as they need to be able to understand genetic test results, its implications for the patient and family, and explain genetic test results to their family members \* No persons with a known psychiatric or documented developmental disorder that affects cognitive or emotional functions to the extent that the capacity for judgment and reason is significantly diminished, such that they cannot participate based on the judgment of the treating physician
12. STEP 2 PROBANDS: Probands positive for a pathogenic germline variant (PGV) in a cancer susceptibility gene

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (299 Sites)

• Anchorage Associates in Radiation Medicine — Anchorage, Alaska
• Alaska Breast Care and Surgery LLC — Anchorage, Alaska
• Alaska Oncology and Hematology LLC — Anchorage, Alaska
• Alaska Women's Cancer Care — Anchorage, Alaska
• Katmai Oncology Group — Anchorage, Alaska
• Providence Alaska Medical Center — Anchorage, Alaska
• Fairbanks Memorial Hospital — Fairbanks, Alaska
• Cancer Center at Saint Joseph's — Phoenix, Arizona
• Mercy Hospital Fort Smith — Fort Smith, Arkansas
• CARTI Cancer Center — Little Rock, Arkansas
• Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California
• Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California
• Mercy Cancer Center - Carmichael — Carmichael, California
• Mercy San Juan Medical Center — Carmichael, California
• Mercy Cancer Center - Elk Grove — Elk Grove, California
• Mercy Cancer Center — Merced, California
• Providence Queen of The Valley — Napa, California
• Mercy Cancer Center - Rocklin — Rocklin, California
• Mercy Cancer Center - Sacramento — Sacramento, California
• Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California
• Mission Hope Medical Oncology - Santa Maria — Santa Maria, California
• Providence Medical Foundation - Santa Rosa — Santa Rosa, California
• Providence Santa Rosa Memorial Hospital — Santa Rosa, California
• Saint Helena Hospital — St. Helena, California
• Saint Joseph's Medical Center — Stockton, California

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.