🏛️ Verified NIH Record • Updated 2026-03-12

IH, Brain Health, and T2D (NCT07173543)

🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol Sponsor: Darren P Casey

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to use a randomized, placebo-controlled study design to rigorously examine the therapeutic potential of intermittent hypoxia (IH) for improving cerebrovascular health in older adults with and without type 2 diabetes mellitus (T2DM).

Who can join: To join this study, participants generally need to meet the listed inclusion criteria (4 items) and avoid the listed exclusions (25 items).

Location: University of Iowa — Iowa City, Iowa

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Check every box below. If you can check all of them, you may meet the study's basic screening requirements (final eligibility is confirmed by the site team).

Usually NOT eligible if any of the following apply:

  • Exclusion criteria:
  • diagnosis of type 2 diabetes \< 1 year prior to enrollment
  • HbA1c \<6.5% or \>10.0%
  • body mass index \> 40 kg/m 2
  • incident cardiovascular events in the last year (heart attack, stroke)
  • symptomatic coronary artery disease and/or heart failure
  • uncontrolled hypertension
  • obstructive sleep apnea
  • pulmonary disease
  • dementia
  • renal impairment with creatinine clearance (eGFR) of \<60 ml/min
  • smoking or history of smoking within past one year 30 nondiabetic control subjects will also be studied. Inclusion criteria:

🔍 Extracted verbatim from the official NIH eligibility criteria. Always confirm with the study coordinator.

📍 All Participating Trial Locations (1 Sites)

  • University of Iowa — Iowa City, Iowa

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
🏛️ View Official NIH Record ↗